Advances in dendritic cell-based vaccine of cancer

X Zhang, JR Gordon, J Xiang - Cancer Biotherapy and …, 2002 - liebertpub.com
Dendritic cells (DCs) are potent antigen presenting cells that exist in virtually every tissue,
and from which they capture antigens and migrate to secondary lymphoid organs where …

Dendritic cell–based immunotherapy: state of the art and beyond

KF Bol, G Schreibelt, WR Gerritsen, IJM De Vries… - Clinical cancer …, 2016 - AACR
Dendritic cell (DC) vaccination in cancer patients aims to induce or augment an effective
antitumor immune response against tumor antigens and was first explored in a clinical trial …

Antitumor dendritic cell–based vaccines: lessons from 20 years of clinical trials and future perspectives

J Constantino, C Gomes, A Falcão, MT Cruz… - Translational …, 2016 - Elsevier
Dendritic cells (DCs) are versatile elements of the immune system and are best known for
their unparalleled ability to initiate and modulate adaptive immune responses. During the …

[PDF][PDF] Dendritic cell-based vaccines in cancer immunotherapy: an update on clinical and immunological results.

WJ Lesterhuis, IJM de Vries, GJ Adema, CJA Punt - 2004 - repository.ubn.ru.nl
The immunogenicity of tumors has been established. Aspecific stimulation of immunity, such
as by cytokine therapy, has been shown to induce durable clinical remissions in metastatic …

Dendritic cells in cancer immunotherapy

M Gunzer, S Grabbe - Critical Reviews™ in Immunology, 2001 - dl.begellhouse.com
Antigen presentation is a critical regulatory element for the induction of cellular immune
responses. Thus, one of the principal current goals of tumor immunotherapy is to control and …

Trial watch: dendritic cell-based anticancer immunotherapy

AD Garg, M Vara Perez, M Schaaf, P Agostinis… - …, 2017 - Taylor & Francis
Dendritic cell (DC)-based vaccines against cancer have been extensively developed over
the past two decades. Typically DC-based cancer immunotherapy entails loading patient …

Dendritic cell-based vaccine research against cancer

N Mody, S Dubey, R Sharma, U Agrawal… - Expert review of clinical …, 2015 - Taylor & Francis
Therapeutic vaccines that treat cancers with the help of the patient's own immune system
signify a feasible option for active immunotherapy against the disease. Dendritic cells (DCs) …

Dendritic cells: are they clinically relevant?

K Palucka, H Ueno, L Roberts, J Fay… - The Cancer …, 2010 - journals.lww.com
Cancer vaccines have undergone a renaissance because of recent clinical trials showing
promising immunologic data and some clinical benefit to patients. Current trials exploiting …

Dendritic cell vaccines for cancer therapy

GM Sprinzl, L Kacani… - Cancer …, 2001 - cancertreatmentreviews.com
Dendritic cells (DC) are professional antigen-presenting cells whose primary function is the
initiation of immune response. Based on the finding that the immune system usually fails to …

Dendritic cell-based vaccine efficacy: aiming for hot spots

GA Pizzurro, MM Barrio - Frontiers in immunology, 2015 - frontiersin.org
Many approaches for cancer immunotherapy have targeted dendritic cells (DCs), directly or
indirectly, for the induction of antitumor immune responses. DC-based vaccines have been …