Venous thromboembolism (VTE) is the formation of a blood clot in, most commonly, the deep
veins of the lower extremities and the pulmonary circulation. VTE is a prevalent disease …

Background Venous thromboembolism (VTE) is a frequent cardiovascular disease with
severe complications, including recurrence and death. There is a great need for alternative …

Background Negatively charged procoagulant phospholipids, phosphatidylserine (PS) in
particular, are vital to coagulation and expressed on the surface membrane of extracellular …

Growing evidence supports a role for extracellular vesicles (EVs) in haemostasis and
thrombosis due to exposure of negatively charged procoagulant phospholipids (PPL) …

Abstract Background Extracellular vesicles (EVs), in particular those derived from activated
platelets, are associated with a risk of future venous thromboembolism. Objectives To study …

Abstract Introduction: Venous thromboembolism (VTE), encompassing pulmonary embolism
(PE) and deep vein thrombosis (DVT), is a major contributor to global morbidity and …

Extracellular vesicles (EVs) participate in thrombosis via the functions of molecule
expression on their surfaces, including tissue factor (TF) and phosphatidylserine (PS). TF is …

Tissue factor (TF) is the main initiator of coagulation and procoagulant phospholipids (PPL)
are key components in promoting coagulation activity in blood. Both TF and PPL may be …

Antiphospholipid syndrome (APS) is a systemic autoimmune disease, characterized by
thrombosis, obstetric complications and the presence of antiphospholipid antibodies (aPL) …

Background Statins are thought to have pleiotropic properties, including anticoagulant
effects, in addition to reducing lipoprotein (LDL) levels. Plasma extracellular vesicles (EVs) …