Platelet extracellular vesicles as biomarkers for arterial thrombosis

A Gasecka, AN Böing, KJ Filipiak, R Nieuwland - Platelets, 2017 - Taylor & Francis
Arterial thrombosis is a major and global cause of human death and disability. Considering
the socioeconomic costs of arterial thrombosis, identification of biomarkers to predict and …

Lipid profile is associated with risk of thrombotic complications

A García-Raso, GS Ene… - Thrombosis and …, 2013 - thieme-connect.com
Venous thromboembolism (VTE) is a leading cause of morbidity and mortality worldwide (1).
The most common complications of the disease are thrombotic recurrence, post-thrombotic …

Procoagulant activity, but not number, of microparticles increases with age and in individuals after a single venous thromboembolism

BAL Owen, A Xue, JA Heit, WG Owen - Thrombosis research, 2011 - Elsevier
The Calibrated Automated Thrombogram (CAT), a plate-based assay that measures
thrombin generation and inhibition in plasma samples, is modified to measure the …

Extracellular vesicles in the antiphospholipid syndrome

S Chaturvedi, R Alluri… - Seminars in thrombosis …, 2018 - thieme-connect.com
Antiphospholipid antibodies (aPL), particularly those directed against β 2-glycoprotein I,
cause activation of vascular cells (endothelial cells, platelets, monocytes) and release of …

[HTML][HTML] A simple flow cytometry method improves the detection of phosphatidylserine‐exposing extracellular vesicles

N Arraud, C Gounou, R Linares, AR Brisson - Journal of Thrombosis and …, 2015 - Elsevier
Background Plasma contains cell‐derived extracellular vesicles (EVs), which participate in
physiopathological processes and have potential applications as disease biomarker …

[HTML][HTML] Elevated plasma levels of P‐selectin glycoprotein ligand‐1‐positive microvesicles in patients with unprovoked venous thromboembolism

S Jamaly, MG Basavaraj, I Starikova, R Olsen… - Journal of Thrombosis …, 2018 - Elsevier
Essentials• PSGL‐1+ microvesicles (MVs) may be important in venous thromboembolism
(VTE).• We measured plasma levels and parental origin of PSGL‐1+ MVs in patients with …

Response: Comment on “Significant decrease in plasma D‐dimer levels and mean platelet volume after a 3‐month treatment with rosuvastatin in patients with venous …

R Irilouzadian - researchgate.net
In our study entitled “Significant decrease in plasma D‐dimer levels and mean platelet
volume after a 3‐month treatment with rosuvastatin in patients with venous …

... relationship between dislipidemia and thrombosis yet unproven

G Lippi, G Guidi - Blood Coagulation & Fibrinolysis, 2001 - journals.lww.com
There is unequivocal scientific evidence that lipid and lipoprotein disorders play a pivotal
role in genesis, progression and complication of arterial thrombosis [1]. However, a causal …

[HTML][HTML] Mode of induction of platelet-derived extracellular vesicles is a critical determinant of their phenotype and function

PM Ferreira, E Bozbas, SD Tannetta, N Alroqaiba… - Scientific Reports, 2020 - nature.com
Platelet-derived extracellular vesicles (PDEVs) are the most abundant amongst all types of
EVs in the circulation. However, the mechanisms leading to PDEVs release, their role in …

[引用][C] MP's and VTE's: Fact or fiction

AP Owens, N Mackman - Thrombosis research, 2011 - thrombosisresearch.com
In this issue, Bucciarelli and colleagues [1] determine if microparticles (MPs) are an
independent risk factor for unprovoked venous thromboembolism (VTE) in a case-control …