Comparative analysis of platelet-derived extracellular vesicles using flow cytometry and nanoparticle tracking analysis

SK George, L Lauková, R Weiss, V Semak… - International Journal of …, 2021 - mdpi.com
Growing interest in extracellular vesicles (EVs) has prompted the advancements of protocols
for improved EV characterization. As a high-throughput, multi-parameter, and single particle …

Circulating levels of tissue factor and the risk of thrombosis associated with antiphospholipid syndrome

LQ Tobaldini, FT Arantes, S da Silva Saraiva… - Thrombosis …, 2018 - Elsevier
The mechanisms behind the severe hypercoagulable state in antiphospholipid syndrome
(APS) have not yet been fully elucidated. Knowledge on the etiology of thrombosis in APS is …

Extracellular vesicles and antiphospholipid syndrome: state-of-the-art and future challenges

U Štok, S Čučnik, S Sodin-Šemrl, P Žigon - International Journal of …, 2021 - mdpi.com
Antiphospholipid syndrome (APS) is a systemic autoimmune disorder characterized by
thromboembolism, obstetric complications, and the presence of antiphospholipid antibodies …

[引用][C] The microparticle‐specific procoagulant phospholipid activity changes with age

V Karlaftis, C Attard, R Summerhayes… - … journal of laboratory …, 2014 - Wiley Online Library
Sir, Procoagulant microparticles (MPs) are small membrane vesicles shed from the plasma
membrane surface and which express a variety of phospholipids and proteins specific to the …

Differential effects of physiological agonists on the proteome of platelet‐derived extracellular vesicles

MJ Moon, A Rai, P Sharma, H Fang, JD McFadyen… - …, 2024 - Wiley Online Library
Arterial thrombosis manifesting as heart attack and stroke is the leading cause of death
worldwide. Platelets are central mediators of thrombosis that can be activated through …

Association of Circulating Platelet Extracellular Vesicles and Pulse Wave Velocity with Cardiovascular Risk Estimation

MP Schlaich, LM Lugo-Gavidia, J Nolde… - Available at SSRN … - papers.ssrn.com
Background: Elevated circulating platelet-derived extracellular vesicles (EV) have been
reported in conditions associated with thrombotic risk. The present study aimed to assess …

Platelet-released extracellular vesicle characteristics differ in chronic and in acute heart disease

A Vilella-Figuerola, A Cordero, S Mirabet… - Thrombosis and …, 2023 - thieme-connect.com
Background Extracellular vesicles (EVs), shed in response to cell activation, stress, or injury,
are increased in the blood of patients with cardiovascular disease. EVs are characterized by …

Platelet tissue factor activity and membrane cholesterol are increased in hypercholesterolemia and normalized by rosuvastatin, but not by atorvastatin

O Panes, C González, P Hidalgo, JP Valderas… - Atherosclerosis, 2017 - Elsevier
Background and aims High plasma LDL-cholesterol (LDL-C) and platelet responses have
major pathogenic roles in atherothrombosis. Thus, statins and anti-platelet drugs constitute …

Platelet function as a risk factor for venous thromboembolism in the Framingham Heart Study

MK Puurunen, SJ Hwang, CJ O'Donnell, G Tofler… - Thrombosis research, 2017 - Elsevier
Introduction The relationship of venous thromboembolism (VTE) with platelet reactivity is
unclear. Platelet function plays a key role in arterial thrombosis. Evidence suggests …

Platelet extracellular vesicles: beyond the blood

F Puhm, E Boilard, KR Machlus - Arteriosclerosis, thrombosis, and …, 2021 - Am Heart Assoc
Extracellular vesicles (EVs) are a means of cell-to-cell communication and can facilitate the
exchange of a broad array of molecules between adjacent or distant cells. Platelets are …