Objective: American Indians experience substantial health disparities relative to the US
population, including vascular brain aging. Poorer cognitive test performance has been …

Objectives To examine the association between vascular pathology and rate of cognitive
decline in older adults independent of Alzheimer's disease (AD) pathology. Design …

Objective To investigate the associations among brain morphologic changes as seen on
magnetic resonance imaging (MRI), cerebrovascular risk (CVR), and clinical diagnosis and …

We previously reported that pathologic measures of arteriosclerosis (AS), cerebral infarction,
and Alzheimer's disease (AD) are independently correlated with cortical gray matter (CGM) …

Background: Current studies suggest an interaction between vascular mechanisms and
neurodegenerative processes that leads to late-onset Alzheimer disease (AD). We tested …

Objective To investigate the associations between lifestyle and vascular risk factors and
changes in Alzheimer's disease (AD) biomarkers (beta-amyloid load via 11C-PiB PET …

In cognitively normal (CN) elderly individuals, white matter hyperintensities (WMH) are
commonly viewed as a marker of cerebral small vessel disease (SVD). SVD is due to …

Objective: To examine the association between prevalent cerebral abnormalities identified
on MRI and cognitive functioning in a predominantly middle-aged, population-based study …

Objective: To investigate the combined ability of hippocampal volumes, 1H magnetic
resonance spectroscopy (MRS) metabolites, and cerebrovascular disease to predict the risk …

Cortical atrophy and brain vascular disease are both associated with dementia, but there are
only limited pathological data on the association of brain vascular disease with cortical …