Low folate levels are associated with reduced risk of colorectal cancer in a population with low folate status

B Gylling, B Van Guelpen, J Schneede, J Hultdin… - … Biomarkers & Prevention, 2014 - AACR
Background: A diet rich in folate is associated with a reduced colorectal cancer risk, whereas
the role of circulating levels is less clear. The aim of this study was to relate prediagnostic …

Association between serum folate level and cervical cancer: a meta-analysis

X Zhou, Y Meng - Archives of gynecology and obstetrics, 2016 - Springer
Purpose The aim of this study was to evaluate the association between serum folate level
and cervical cancer. Methods PubMed, Medline, Springer, Elsevier Science Direct …

[HTML][HTML] Will mandatory folic acid fortification prevent or promote cancer?

YI Kim - The American journal of clinical nutrition, 2004 - Elsevier
An overwhelming body of evidence for a protective effect of periconceptional folic acid
supplementation against neural tube defects (NTDs) led to mandatory folic acid fortification …

Red blood cell folate and plasma folate are not associated with risk of incident colorectal cancer in the W omen's H ealth I nitiative observational study

ML Neuhouser, TYD Cheng… - … Journal of Cancer, 2015 - Wiley Online Library
The relationship between folate and colorectal cancer (CRC) risk is unclear. We investigated
the association of two biomarkers of folate status, plasma folate and red blood cell (RBC) …

MTHFR polymorphisms, dietary folate intake and risks to breast cancer

CM Gao, T Kazuo, JH Tang, HX Cao… - … yu fang yi xue za zhi …, 2009 - europepmc.org
Objective To evaluate the relationship between dietary folate intake and genetic
polymorphisms of 5, 10-methylenetetrahydrofolate reductase (MTHFR) with reference to …

Effect of combined folic acid, vitamin B6, and vitamin B12 on cancer risk in women: a randomized trial

SM Zhang, NR Cook, CM Albert, JM Gaziano… - Jama, 2008 - jamanetwork.com
Context Folate, vitamin B 6, and vitamin B 12 are thought to play an important role in cancer
prevention. Objective To evaluate the effect of combined folic acid, vitamin B 6, and vitamin …

Association between folate intake and the risk of lung cancer: a dose-response meta-analysis of prospective studies

YF Zhang, L Zhou, HW Zhang, AJ Hou, HF Gao… - PloS one, 2014 - journals.plos.org
Background Studies have reported inconsistent results regarding the existence of an
association between folate intake and the risk of lung cancer. The purpose of this study was …

[HTML][HTML] Folate intake, post–folic acid grain fortification, and pancreatic cancer risk in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial

BM Oaks, KW Dodd, CL Meinhold, L Jiao… - The American journal of …, 2010 - Elsevier
Background: Folate plays a critical role in DNA methylation, synthesis, and repair. Several
epidemiologic studies suggest that higher folate intake is associated with decreased …

Cancer risk with folic acid supplements: a systematic review and meta-analysis

TN Wien, E Pike, T Wisløff, A Staff, S Smeland… - BMJ open, 2012 - bmjopen.bmj.com
Objective To explore if there is an increased cancer risk associated with folic acid
supplements given orally. Design Systematic review and meta-analysis of controlled studies …

Dietary folate consumption and risk of ovarian cancer: a prospective cohort study

SAN Silvera, M Jain, GR Howe, AB Miller… - European journal of …, 2006 - journals.lww.com
Deficient dietary folate intake may be associated with increased cancer risk in humans
owing to DNA damage resulting from impaired nucleotide excision repair. It is conceivable …