Benzalkonium chloride (BAC), a quaternary ammonium compound, is a common
antimicrobial agent used in many everyday household products. It kills on contact most …

Since the introduction of β 2-selective adrenergic drugs in the 1960s and the development of
the metered-dose inhaler (MDI) delivery system, these agents have rapidly become the most …

Benzalkonium chloride (BAC) added to nebulized albuterol may induce bronchospasm. The
objective of this study was to determine the availability of BAC-containing nebulized …

In a recently published systematic review and meta-analysis, which included 30 trials
representing 1992 infants with bronchiolitis, the authors concluded that bronchodilators such …

The guideline authors imply that our randomized controlled trial in 703 children with
bronchiolitis supports their assertion that “clinical scores may vary from between observers” …

For convenience, many pediatric hospitals are preparing solutions for continuous nebulized
albuterol using the 0.5% 20‐ml multidose albuterol dropper bottle. This product contains …

METHODS: We performed a retrospective cohort study comparing the clinical outcomes of
patients< 18 years of age receiving continuous nebulized albuterol with and without BAC …

Although all 50 states permit children with asthma to self-carry personal inhalers, access to
emergency inhalers may be as low as 14%. 1 Every child could have access when needed if …

We appreciate Dr DiTraglia's observation that there appeared to be a conflict between the
conclusions of our systematic reviews on the diagnosis and treatment of bronchiolitis1, 2 …

Albuterol is routinely administered via continuous nebulization for the treatment of status
asthmaticus. However, the preservative benzalkonium chloride (BAC) is present in some but …