In obesity, skeletal muscle mitochondrial activity changes to cope with increased nutrient
availability. Autophagy has been proposed as an essential mechanism involved in the …

Lipid overload of the mitochondria is linked to the development of insulin resistance in
skeletal muscle which may be a contributing factor to the progression of type 2 diabetes …

Skeletal muscle possesses dramatic metabolic plasticity that allows for the rapid adaptation
in cellular energy transduction to meet the demands of the organism. Obesity elicits changes …

Autophagy is stimulated by exercise in several tissues; yet the role of skeletal and cardiac
muscle-specific autophagy on the benefits of exercise training remains incompletely …

The quality of mitochondria in skeletal muscle is essential for maintaining metabolic
homeostasis during adaptive stress responses. However, the precise control mechanism of …

Skeletal muscle is composed of bundles of muscle fibers with distinctive characteristics.
Oxidative muscle fiber types contain higher mitochondrial content, relying primarily on …

The purpose of this study is to determine whether moderate aerobic exercise training
improves high‐fat diet‐induced alterations in mitochondrial function and structure in the …

In most cells, mitochondria are highly dynamic organelles that constantly fuse, divide and
move. These processes allow mitochondria to redistribute in a cell and exchange contents …

Background Type 2 diabetes mellitus and muscle insulin resistance have been associated
with reduced capacity of skeletal muscle mitochondria, possibly as a result of increased …

Mitochondrial dysfunction in skeletal muscle has been implicated in the development of
insulin resistance and type 2 diabetes. Considering the importance of mitochondrial …