Amiodarone is a unique and complex drug. It was synthesized in the early 1960s as a
vasodilator/antianginal agent but was subsequently found to be a highly effective …

Objectives. To review the historical development of amiodarone and the changing
perceptions of the drug, and discuss its electrophysiologic, pharmacologic, and …

Amiodarone has been used for more than half a century, and has multiple
electrophysiological and hemodynamic effects. It is one of the most effective antiarrhythmics …

Amiodarone is an effective antiarrhythmic medication frequently used in practice for both
ventricular and atrial arrhythmias. Though classified as a class III antiarrhythmic, it affects all …

Amiodarone Therapy. Amiodarone is a unique compound, with actions of all four
antiarrhythmic drug classes. It has been used effectively to treat a broad range of ventricular …

Amiodarone is a benzofuran derivative that has been effective for the treatment of both
supraventricular and ventricular tachyarrhythmias. It has a large volume of distribution …

Amiodarone, an iodinated benzofuran derivative, introduced in 1960's as an anti-anginal
agent, emerged as a potent anti-arrhythmic agent by 1970's and is currently one of the most …

Objectives. To review the clinical efficacy and role of amiodarone in the management of
supraventricular and ventricular arrhythmias and its effects on mortality. Methods. Review of …

Amiodarone is a potent and versatile antiarrhythmic. Despite side effects involving the lungs,
heart, thyroid, and other organs, it is effective in the treatment of refractory atrial and …

Amiodarone is an effective antiarrhythmic drug for supra-ven-tri-cular and ventricular
arrhythmias. A majority of patients treated with amiodarone suffer from mild adverse events …