Liver-expressed antimicrobial peptide 2 (LEAP-2), originally described as an antimicrobial
peptide, has recently been recognized as an endogenous blocker of growth hormone …

Liver-expressed antimicrobial peptide 2 (LEAP-2), the endogenous noncompetitive
allosteric antagonist of the growth hormone secretagogue receptor 1a (GHSR1a), was …

Data gleaned recently shows that ghrelin, a stomach derived peptide, and liver-expressed-
antimicrobial peptide 2 (LEAP-2) play opposite roles on food intake. However, the data …

The ghrelin receptor or growth hormone secretagogue receptor (GHSR) is a G-protein-
coupled receptor that controls growth hormone and insulin secretion, food intake, and …

Ghrelin, a stomach-derived peptide, promotes feeding and growth hormone (GH) secretion.
A recent study identified liver-expressed antimicrobial peptide 2 (LEAP2) as an endogenous …

Ghrelin, an appetite-stimulatory hormone secreted by the stomach, was discovered as a
ligand for the growth hormone secretagogue receptor (GHSR). Through GHSR, ghrelin …

Objective The hormone liver-expressed antimicrobial peptide-2 (LEAP2) is a recently
identified antagonist and an inverse agonist of the growth hormone secretagogue receptor …

Liver‐expressed antimicrobial peptide 2 (LEAP 2) is a highly conserved secretory peptide
first isolated in 2003. However, its exact biological functions remained elusive until a recent …

Ghrelin is secreted in the stomach during fasting and targets the growth hormone
secretagogue receptor (GHSR1a) in the hypothalamus and brainstem to exert its orexigenic …

The gastric hormone ghrelin stimulates food intake and increases plasma glucose through
activation of the growth hormone secretagogue receptor (GHSR). Liver-expressed …