The ironclad truth: how in vivo transcriptomics and in vitro mechanistic studies shape our understanding of Neisseria gonorrhoeae gene regulation during mucosal …

MR Moreau, P Massari, CA Genco - Pathogens and disease, 2017 - academic.oup.com
Neisseria gonorrhoeae is one of the most prevalent sexually transmitted infections
worldwide. This obligate human pathogen has been extensively studied in vitro, where …

Molecular Regulatory Mechanisms Drive Emergent Pathogenetic Properties of Neisseria gonorrhoeae

A Sunkavalli, R McClure, C Genco - Microorganisms, 2022 - mdpi.com
Neisseria gonorrhoeae is the causative agent of the sexually transmitted infection (STI)
gonorrhea, with an estimated 87 million annual cases worldwide. N. gonorrhoeae …

The gonococcal transcriptome during infection of the lower genital tract in women

R McClure, K Nudel, P Massari, B Tjaden, X Su… - PloS one, 2015 - journals.plos.org
Gonorrhea is a highly prevalent disease resulting in significant morbidity worldwide, with an
estimated 106 cases reported annually. Neisseria gonorrhoeae, the causative agent of …

Transcriptome analysis of Neisseria gonorrhoeae during natural infection reveals differential expression of antibiotic resistance determinants between men and …

K Nudel, R McClure, M Moreau, E Briars, AJ Abrams… - Msphere, 2018 - Am Soc Microbiol
Neisseria gonorrhoeae is a bacterial pathogen responsible for the sexually transmitted
infection gonorrhea. Emergence of antimicrobial resistance (AMR) of N. gonorrhoeae …

Global network analysis of Neisseria gonorrhoeae identifies coordination between pathways, processes, and regulators expressed during human infection

R McClure, A Sunkavalli, PM Balzano, P Massari… - Msystems, 2020 - Am Soc Microbiol
Neisseria gonorrhoeae is a Gram-negative diplococcus that is responsible for the sexually
transmitted infection gonorrhea, a high-morbidity disease in the United States and …

[PDF][PDF] Transcriptome analysis of Neisseria gonorrhoeae during natural infection reveals differential expression of antibiotic resistance determinants between men and …

K Nudel, R McClure, M Moreau, E Briars, AJ Abrams… - 2018 - core.ac.uk
Neisseria gonorrhoeae is a bacterial pathogen responsible for the sexually transmitted
infection gonorrhea. Emergence of antimicrobial resistance (AMR) of N. gonorrhoeae …

Expression capable library for studies of Neisseria gonorrhoeae, version 1.0

T Brettin, MR Altherr, Y Du, RM Mason, A Friedrich… - BMC microbiology, 2005 - Springer
Background The sexually transmitted disease, gonorrhea, is a serious health problem in
developed as well as in developing countries, for which treatment continues to be a …

Transcriptional landscape and essential genes of Neisseria gonorrhoeae

CW Remmele, Y Xian, M Albrecht… - Nucleic acids …, 2014 - academic.oup.com
The WHO has recently classified Neisseria gonorrhoeae as a super-bacterium due to the
rapid spread of antibiotic resistant derivatives and an overall dramatic increase in infection …

Identification of sRNAs expressed by the human pathogen Neisseria gonorrhoeae under disparate growth conditions

R McClure, B Tjaden, C Genco - Frontiers in microbiology, 2014 - frontiersin.org
In the last several years, bacterial gene regulation via small RNAs (sRNAs) has been
recognized as an important mechanism controlling expression of essential proteins that are …

Expression of the gonococcal global regulatory protein Fur and genes encompassing the Fur and iron regulon during in vitro and in vivo infection in women

S Agarwal, S Sebastian, B Szmigielski… - Journal of …, 2008 - Am Soc Microbiol
The ferric uptake regulatory protein, Fur, functions as a global regulatory protein of gene
transcription in the mucosal pathogen Neisseria gonorrhoeae. We have shown previously …