Gonorrhea is a sexually transmitted disease with a high morbidity burden. Despite having
guidelines for its treatment, the incidence of the disease follows an increasing trend …

Objectives Drug-resistant Neisseria gonorrhoeae are now a global public health threat.
Direct transmission of antibiotic-resistant gonococci between individuals has been proposed …

Gonorrhea, caused by the human pathogen Neisseria gonorrhoeae, is a severe public
health problem worldwide with more than 82 million new infections each year. N …

The type IV secretion system of Neisseria gonorrhoeae translocates single-stranded DNA
into the extracellular space, facilitating horizontal gene transfer and initiating biofilm …

Background The prevalence of Neisseria gonorrhoeae (GC) isolates with elevated minimum
inhibitory concentrations to various antibiotics continues to rise in the United States and …

Abstract Background Multidrug-resistant Neisseria gonorrhoeae strains are prevalent,
threatening gonorrhoea treatment globally, and understanding of emergence, evolution, and …

Neisseria gonorrhoeae is an exquisitely adapted, strictly human pathogen and the causative
agent of the sexually transmitted infection gonorrhea. This ancient human disease remains a …

Infection with the human-specific bacterial pathogen Neisseria gonorrhoeae triggers a
potent, local inflammatory response driven by polymorphonuclear leukocytes (neutrophils or …

Neisseria gonorrhoeae is the etiological factor of the sexually transmitted gonorrhea disease
that may lead, under specific conditions, to systemic infections. The gonococcal genome …

Due to the increased resistance to all available antibiotics and the lack of vaccines,
Neisseria gonorrhoeae (the gonococcus) poses an urgent threat. Although the mechanisms …