Low-resolution pressure reactivity index and its derived optimal cerebral perfusion pressure in adult traumatic brain injury: a CENTER-TBI study

L Riemann, E Beqiri, P Smielewski, M Czosnyka… - Critical care, 2020 - Springer
Background After traumatic brain injury (TBI), brain tissue can be further damaged when
cerebral autoregulation is impaired. Managing cerebral perfusion pressure (CPP) according …

Early identification of bleeding in trauma patients: external validation of traumatic bleeding scores in the Swiss Trauma Registry

A Costa, PN Carron, T Zingg, I Roberts, FX Ageron… - Critical Care, 2022 - Springer
Background Early identification of bleeding at the scene of an injury is important for triage
and timely treatment of injured patients and transport to an appropriate facility. The aim of …

Low hemoglobin is associated with poor functional outcome after non-traumatic, supratentorial intracerebral hemorrhage

J Diedler, M Sykora, P Hahn, K Heerlein, MN Schölzke… - Critical care, 2010 - Springer
Introduction The impact of anemia on functional outcome and mortality in patients suffering
from non-traumatic intracerebral hemorrhage (ICH) has not been investigated. Here, we …

Improved outcomes from the administration of progesterone for patients with acute severe traumatic brain injury: a randomized controlled trial

G Xiao, J Wei, W Yan, W Wang, Z Lu - Critical care, 2008 - Springer
Background Severe traumatic brain injury (TBI) has been increasing with greater incidence
of injuries from traffic or sporting accidents. Although there are a number of animal models of …

Effect of propranolol and clonidine after severe traumatic brain injury: a pilot randomized clinical trial

MF Nordness, AW Maiga, LD Wilson, T Koyama… - Critical Care, 2023 - Springer
Objective To evaluate the safety, feasibility, and efficacy of combined adrenergic blockade
with propranolol and clonidine in patients with severe traumatic brain injury (TBI) …

Disseminated intravascular coagulation with increased fibrinolysis during the early phase of isolated traumatic brain injury

T Wada, S Gando, K Maekaw, K Katabami… - Critical Care, 2017 - Springer
Background There is evidence to demonstrate that the coagulopathy which occurs in
patients with traumatic brain injury coincides with disseminated intravascular coagulation …

[HTML][HTML] C-reactive protein-albumin ratio and procalcitonin in predicting intensive care unit mortality in traumatic brain injury

C Gürsoy, G Gürsoy… - Acute and Critical Care, 2022 - synapse.koreamed.org
Background Prediction of intensive care unit (ICU) mortality in traumatic brain injury (TBI),
which is a common cause of death in children and young adults, is important for injury …

Fluid proteomics of CSF and serum reveal important neuroinflammatory proteins in blood–brain barrier disruption and outcome prediction following severe traumatic …

C Lindblad, E Pin, D Just, F Al Nimer, P Nilsson… - Critical Care, 2021 - Springer
Background Severe traumatic brain injury (TBI) is associated with blood–brain barrier (BBB)
disruption and a subsequent neuroinflammatory process. We aimed to perform a multiplex …

Brain tissue oxygen monitoring in traumatic brain injury—part II: isolated and combined insults in relation to outcome

T Svedung Wettervik, E Beqiri, A Hånell, SY Bögli… - Critical Care, 2023 - Springer
Background The primary aim was to explore the concept of isolated and combined threshold-
insults for brain tissue oxygenation (pbtO2) in relation to outcome in traumatic brain injury …

Trauma complications and in-hospital mortality: failure-to-rescue

T Abe, A Komori, A Shiraishi, T Sugiyama, H Iriyama… - Critical Care, 2020 - Springer
Background Reducing medical errors and minimizing complications have become the focus
of quality improvement in medicine. Failure-to-rescue (FTR) is defined as death after a …