Permanent threshold elevation after noise exposure or aging is caused by loss of sensory
cells; however, animal studies show that hair cell loss is often preceded by degeneration of …

Hearing loss caused by noise exposure, ototoxic drugs, or aging results from the loss of
sensory cells, as reflected in audiometric threshold elevation. Animal studies show that loss …

Listeners with normal audiometric thresholds can still have suprathreshold deficits, for
example, in the ability to discriminate sounds in complex acoustic scenes. One likely source …

Recent studies on animal models have shown that noise exposure that does not lead to
permanent threshold shift (PTS) can cause considerable damage around the synapses …

Previous work in animals with recovered hearing thresholds but permanent inner hair cell
synapse loss after noise have suggested initial vulnerability of low spontaneous rate (SR) …

Evidence from animal and human studies suggests that moderate acoustic exposure,
causing only transient threshold elevation, can nonetheless cause “hidden hearing loss” that …

Objectives: Recent animal studies demonstrated that cochlear synaptopathy, a partial loss of
inner hair cell-auditory nerve fiber synapses, can occur in response to noise exposure …

The healthy auditory system enables communication in challenging situations with high
levels of background noise. Yet, despite normal sensitivity to pure tones, many listeners …

Purpose Complaints of auditory perceptual deficits, such as tinnitus and difficulty
understanding speech in background noise, among individuals with clinically normal …

Animal studies have demonstrated that noise exposure can lead to the loss of the synapses
between the inner hair cells and their afferent auditory nerve fiber targets without impacting …