Recent evidence has shown that noise-induced damage to the synapse between inner hair
cells (IHCs) and type I afferent auditory nerve fibers (ANFs) may occur in the absence of …

In rodents, exposure to high-level noise can destroy synapses between inner hair cells and
auditory nerve fibers, without causing hair cell loss or permanent threshold elevation. Such …

Animal studies demonstrate that noise exposure can permanently damage the synapses
between inner hair cells and auditory nerve fibers, even when outer hair cells are intact and …

Many individuals with seemingly normal hearing abilities struggle to understand speech in
noisy backgrounds. To understand why this might be the case, we investigated the neural …

Speech perception in background noise is a common challenge across individuals and
health conditions (eg, hearing impairment, aging, etc.). Both behavioral and physiological …

Noise exposure that causes a temporary threshold shift but no permanent threshold shift can
cause degeneration of synaptic ribbons and afferent nerve fibers, with a corresponding …

Emerging evidence suggests that cochlear synaptopathy is a common feature of
sensorineural hearing loss, but it is not known to what extent electrophysiological metrics …

A current initiative in auditory neuroscience research is to better understand why some
listeners struggle to perceive speech-in-noise (SIN) despite having normal hearing …

Objectives: Recent studies in animals indicate that even moderate levels of exposure to
noise can damage synaptic ribbons between the inner hair cells and auditory nerve fibers …

Background: Difficulty understanding speech in background noise is a common complaint of
individuals with sensorineural hearing loss. Recent animal studies suggest this difficulty may …