Spinal muscular atrophy (SMA) is an autosomal recessive disease characterized by
degeneration and loss of lower motor neurons in the spinal cord and brainstem. Clinically …

Spinal muscular atrophy (SMA) is a neurodegenerative disease characterized by loss of
motor neurons in the anterior horn of the spinal cord and resultant weakness. The most …

Spinal muscular atrophies (SMA) are frequent autosomal recessive disorders characterized
by degeneration of lower motor neurons. SMA are caused by mutations of the survival of …

Spinal muscular atrophy (SMA) is a devastating genetic disease caused by mutations in the
survival motor neuron 1 (SMN1) gene that encodes SMN protein. Since mid-1990s when the …

Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disorder and
a leading genetic cause of infantile mortality. SMA is caused by mutation or deletion of …

Spinal muscular atrophies (SMA) are characterized by degeneration of lower motor neurons
associated with muscle paralysis and atrophy. Childhood SMA is a frequent recessive …

Spinal muscular atrophy (SMA) is a hereditary neurodegenerative disease caused by
homozygous deletions or mutations in the SMN1 gene on Chr. 5q13. SMA spans from …

Opinion statement Spinal muscular atrophy (SMA) is an autosomal recessive disease
characterized by degeneration of spinal cord motor neurons and muscular atrophy …

Spinal muscular atrophy (SMA) is a progressive neurodegenerative disease with an
autosomal recessive trait of inheritance and great variability of its clinical course–from the …

Spinal muscular atrophy (SMA) is a neurodegenerative disorder caused by mutations in
SMN1 (encoding survival motor neuron protein (SMN)). Reduced expression of SMN leads …