BACKGROUND: Studies have shown that microRNAs play an important role in the
regulation of inflammation-mediated diseases. miRNAs are involved in a series of processes …

Osteoarthritis (OA) is a common chronic degenerative joint disease, with complicated
pathogenic factors and undefined pathogenesis. Various signaling pathways play important …

Osteoarthritis (OA) is the most common joint disease. It is characterized by degenerative
changes of articular cartilage and chondrocyte apoptosis. The prevalence of OA increases …

MicroRNAs are a class of non-coding RNA molecules that regulate the gene expression at
the post-transcription levels. They have been implicated in various important cellular …

Worldwide, osteoarthritis (OA) is the most common cause of joint pain in older people. Many
factors contribute to osteoarthritis' development and progression, including secondary …

Objective To review the regulation and mechanism of the microRNAs (miRNAs) in the bone
and cartilage tissue. Methods Recent literature concerning the regulation and mechanism of …

Osteoarthritis (OA) is characterized by degeneration of articular cartilage, limited
intraarticular inflammation with synovitis, and changes in peri-articular and subchondral …

Objective To summarize the research progress of microRNA (miRNA) in the osteoarthritis
(OA) cartilage matrix degradation. Methods The domestic and foreign related literature about …

Introduction Osteoarthritis (OA) is a common disease worldwide leading to significant
morbidity. The underlying disease process is multifactorial however there is increasing focus …

Osteoarthritis (OA) is one of the most widespread degenerative joint diseases affecting the
elderly. Research into the regulatory mechanisms underlying the pathogenesis of OA is …