Abstract LB-205: A lipoplex-based mRNA nanovaccine for cancer immunotherapy
Z Hongxia, Y Xinru, W Xiaojuan, W Zining, X Feifei… - Cancer Research, 2019 - AACR
Intracellular delivery of messenger RNA (mRNA)-based cancer vaccines have shown great
potential to activate antitumor immune response for cancer prevention and therapy. In vivo …
potential to activate antitumor immune response for cancer prevention and therapy. In vivo …
Delivery of mRNA vaccine with a lipid-like material potentiates antitumor efficacy through Toll-like receptor 4 signaling
H Zhang, X You, X Wang, L Cui… - Proceedings of the …, 2021 - National Acad Sciences
Intracellular delivery of messenger RNA (mRNA)-based cancer vaccine has shown great
potential to elicit antitumor immunity. To achieve robust antitumor efficacy, mRNA encoding …
potential to elicit antitumor immunity. To achieve robust antitumor efficacy, mRNA encoding …
RNA cancer vaccines: developing mRNA nanovaccine with self-adjuvant property for cancer immunotherapy
H Zhang, X Xia - Human Vaccines & Immunotherapeutics, 2021 - Taylor & Francis
Messenger RNA (mRNA)-based cancer vaccine has become a popular approach for
developing personalized and effective antitumor immunotherapy. To achieve robust …
developing personalized and effective antitumor immunotherapy. To achieve robust …
Emerging advances in delivery systems for mRNA cancer vaccines
Z Jiang, Y Xu, G Du, X Sun - Journal of Controlled Release, 2024 - Elsevier
The success of lipid nanoparticles (LNPs) in treating COVID-19 promotes further research of
mRNA vaccines for cancer vaccination. Aiming at overcoming the constraints of currently …
mRNA vaccines for cancer vaccination. Aiming at overcoming the constraints of currently …
mRNA vaccines and their delivery strategies: A journey from infectious diseases to cancer
mRNA vaccines have evolved as promising cancer therapies. These vaccines can encode
tumor-allied antigens, thus enabling personalized treatment approaches. They can also …
tumor-allied antigens, thus enabling personalized treatment approaches. They can also …
Lipid nanoparticle-mediated lymph node–targeting delivery of mRNA cancer vaccine elicits robust CD8+ T cell response
The targeted delivery of messenger RNA (mRNA) to desired organs remains a great
challenge for in vivo applications of mRNA technology. For mRNA vaccines, the targeted …
challenge for in vivo applications of mRNA technology. For mRNA vaccines, the targeted …
Messenger RNA Nanovaccine in Cancer Immunotherapy
M Li, H Zhang - Cancer Nanotechnology, 2022 - Springer
During the past 2 years, messenger RNA (mRNA) nanovaccine has shown its remarkable
antiviral efficacy, rapid manufacture, and good safety profile for preventing coronavirus …
antiviral efficacy, rapid manufacture, and good safety profile for preventing coronavirus …
Hybrid nanovaccine for the co-delivery of the mRNA antigen and adjuvant
J Yang, S Arya, P Lung, Q Lin, J Huang, Q Li - Nanoscale, 2019 - pubs.rsc.org
For efficient cancer vaccines, the antitumor function largely relies on cytotoxic T cells, whose
activation can be effectively induced via antigen-encoding mRNA, making mRNA-based …
activation can be effectively induced via antigen-encoding mRNA, making mRNA-based …
An Overview of Nanoparticle-Based Delivery Platforms for mRNA Vaccines for Treating Cancer
Y Lin, X Chen, K Wang, L Liang, H Zhang - Vaccines, 2024 - mdpi.com
With its unique properties and potential applications, nanoparticle-based delivery platforms
for messenger RNA (mRNA) vaccines have gained significant attention in recent years …
for messenger RNA (mRNA) vaccines have gained significant attention in recent years …
Lipid nanoparticle-based mRNA vaccines: a new frontier in precision oncology
The delivery of lipid nanoparticle (LNP)-based mRNA therapeutics has captured the
attention of the vaccine research community as an innovative and versatile tool for treating a …
attention of the vaccine research community as an innovative and versatile tool for treating a …