Autophagy markers as mediators of lung injury-implication for therapeutic intervention

S Vishnupriya, LCP Dharshini, KM Sakthivel… - Life sciences, 2020 - Elsevier
Lung injury is characterized by inflammatory processes demonstrated as loss of function of
the pulmonary capillary endothelial and alveolar epithelial cells. Autophagy is an …

Autophagy as a double-edged sword in pulmonary epithelial injury: a review and perspective

ZY Li, YF Wu, XC Xu, JS Zhou… - … of Physiology-Lung …, 2017 - journals.physiology.org
Pulmonary epithelial cells form the first line of defense of human airways against foreign
irritants and also represent as the primary injury target of these pathogenic assaults …

Autophagy in the pathogenesis of pulmonary disease

J Araya, H Hara, K Kuwano - Internal Medicine, 2013 - jstage.jst.go.jp
Autophagy is a process of lysosomal self-degradation that helps to maintain the homeostatic
balance between the synthesis, degradation and recycling of cellular proteins and …

Autophagy in pulmonary diseases

SW Ryter, K Nakahira, JA Haspel… - Annual review of …, 2012 - annualreviews.org
(Macro) autophagy provides a membrane-dependent mechanism for the sequestration,
transport, and lysosomal turnover of subcellular components, including proteins and …

[HTML][HTML] Protective features of autophagy in pulmonary infection and inflammatory diseases

K Wang, Y Chen, P Zhang, P Lin, N Xie, M Wu - Cells, 2019 - mdpi.com
Autophagy is a highly conserved catabolic process involving autolysosomal degradation of
cellular components, including protein aggregates, damaged organelles (such as …

Autophagy: a potential therapeutic target in lung diseases

K Nakahira, AMK Choi - American Journal of Physiology …, 2013 - journals.physiology.org
Macroautophagy (hereafter referred to as autophagy) is an evolutionally conserved
intracellular process to maintain cellular homeostasis by facilitating the turnover of protein …

The emerging importance of autophagy in pulmonary diseases

K Mizumura, SM Cloonan, JA Haspel, AMK Choi - Chest, 2012 - Elsevier
Important cellular processes such as inflammation, apoptosis, differentiation, and
proliferation confer critical roles in the pathogenesis of human diseases. In the past decade …

Role of autophagy in lung diseases and ageing

Y Zhang, J Zhang, Z Fu - European Respiratory Review, 2022 - Eur Respiratory Soc
The lungs face ongoing chemical, mechanical, biological, immunological and xenobiotic
stresses over a lifetime. Advancing age progressively impairs lung function. Autophagy is a …

[HTML][HTML] Autophagy in lung disease pathogenesis and therapeutics

SW Ryter, AMK Choi - Redox biology, 2015 - Elsevier
Autophagy, a cellular pathway for the degradation of damaged organelles and proteins, has
gained increasing importance in human pulmonary diseases, both as a modulator of …

Oxidative stress-induced autophagy: role in pulmonary toxicity

R Malaviya, JD Laskin, DL Laskin - Toxicology and applied pharmacology, 2014 - Elsevier
Autophagy is an evolutionarily conserved catabolic process important in regulating the
turnover of essential proteins and in elimination of damaged organelles and protein …