[Frontiers in Bioscience 13, 2814-2832, January 1, 2008] 2814 Stem cells and kidney
organogenesis Takashi Yokoo1,2, Akira Fukui Page 1 [Frontiers in Bioscience 13, 2814-2832 …

Renal failure has a high prevalence and is becoming a public health problem worldwide.
However, the renal replacement therapies such as dialysis are not yet satisfactory for its …

The kidney has the capacity to recover from ischemic and toxic insults. Although there has
been debate about the origin of cells that replace injured epithelial cells, it is now widely …

Both kidney and circulating stem cells participate in kidney regeneration. However, the role
of extrarenal stem cells is at best minimal. 1, 2 The major source of regenerating cells after …

The kidney possesses an impressive regeneration capacity and is the most performant
among all tissues in the body. Yet ischaemic injury to the kidney produces acute tubular …

Adult stem cells have been characterized in several tissues as a subpopulation of cells able
to maintain, generate, and replace terminally differentiated cells in response to physiological …

Stem cells (SC) provide a way to repopulate damaged organs, to deliver genes or growth
factors to privileged sites in the body after gene transfection and to reconstitute organs in …

Previous studies have suggested that CD133+ cells isolated from human kidney biopsies
have the potential to ameliorate injury following intravenous (IV) administration in rodent …

Background Bone marrow (BM) stem cells have been reported to contribute to tissue repair
after kidney injury model. However, there is no direct evidence so far that BM cells can trans …

Background aims. Tissue-specific stem cells are a promising target for kidney regeneration,
because it has been shown that they play a primary role in kidney repair. Several methods …