Background/Aim: This study aimed to measure the DNA methylation state of thousands of
CpG islands in the blood of two monozygotic twins that were discordant for cardiovascular …

Cardiovascular diseases (CVDs) are the leading causes of death worldwide and represent a
substantial economic burden on public health care systems. Epigenetic markers have …

Background Cardiovascular disease (CVD) is the leading cause of death worldwide and
considered one of the most environmentally driven diseases. The role of DNA methylation in …

Background Using genome-wide association studies several genes have been identified
that affect the risk of CAD. However, these genes only explain part of the heritability. There is …

DNA methylation commonly occurs at cytosine-phosphate-guanine sites (CpGs) that can
serve as biomarkers for many diseases. We analyzed whole genome sequencing data to …

Background The epigenetic landscape underlying cardiovascular disease (CVD) is not
completely understood and the clinical value of the identified biomarkers is still limited. We …

DNA methylation plays an important role in the development and etiology of type 2 diabetes;
however, few epigenomic studies have been conducted on twins. Herein, a two-stage study …

Background Short tandem repeat (STR) markers cannot be used to distinguish between
genetically identical monozygotic (MZ) twins, causing problems in a case with an MZ twin as …

Background Systemic studies of association of genome-wide DNA methylated sites with
cardiovascular disease (CVD) in prospective cohorts are lacking. Our aim was to identify …

Background The alteration in the epigenome forms an interface between the genotype and
the environment. Epigenetic alteration is expected to make a significant contribution to the …