Rationale and design of a multi‐center, prospective randomized controlled trial on the effects of sacubitril–valsartan versus enalapril on left ventricular remodeling in …

K Diao, D Wang, Z Chen, X Wu, M Ma, Y Zhu… - Clinical …, 2021 - Wiley Online Library
Background Angiotensin receptor neprilysin inhibitor (ARNI) sacubitril‐valsartan has been
recommended as one of the first‐line therapies in heart failure with reduced ejection fraction …

Impact of sacubitril/valsartan compared with ramipril on cardiac structure and function after acute myocardial infarction: the PARADISE-MI echocardiographic substudy

AM Shah, B Claggett, N Prasad, G Li, M Volquez… - Circulation, 2022 - Am Heart Assoc
Background: Angiotensin-converting enzyme inhibitors attenuate left ventricular (LV)
enlargement after acute myocardial infarction (AMI). Preclinical data suggest similar benefits …

Effect of sacubitril–valsartan on left ventricular remodeling in patients with acute myocardial infarction after primary percutaneous coronary intervention: a systematic …

Y Liu, Y Sun, W Dai - Frontiers in Pharmacology, 2024 - frontiersin.org
Background Sacubitril–valsartan has been widely reported for reducing the risk of
cardiovascular death and improving left ventricular remodeling in patients with heart failure …

Comparison of the efficacy and safety of sacubitril/valsartan versus ramipril in patients with ST-segment elevation myocardial infarction

A Rezq, M Saad, M El Nozahi - The American journal of cardiology, 2021 - Elsevier
The role of sacubitril and/or valsartan in patient with heart failure (HF) is established.
Whether sacubitril and/or valsartan plays a role in improving outcomes in patients after ST …

Rationale and methods of a randomized trial evaluating the effect of neprilysin inhibition on left ventricular remodelling

KF Docherty, RT Campbell, KJM Brooksbank… - ESC Heart …, 2021 - Wiley Online Library
Aims In patients at high risk of heart failure following myocardial infarction (MI) as a result of
residual left ventricular systolic dysfunction (LVSD), the angiotensin receptor neprilysin …

[HTML][HTML] Effects and clinical implications of sacubitril/valsartan on left ventricular reverse remodeling in patients affected by chronic heart failure: a 24-month follow-up

C Paolini, G Mugnai, C Dalla Valle, A Volpiana… - IJC Heart & …, 2021 - Elsevier
Background Compared to angiotensin inhibition, angiotensin-neprilysin “blockade”
improves mortality and reduces hospitalizations in patients with heart failure (HF) with …

[HTML][HTML] A systematic review and meta-analysis of sacubitril-valsartan in the treatment of ventricular remodeling in patients with heart failure after acute myocardial …

X Zhou, H Zhu, Y Zheng, X Tan, X Tong - Frontiers in Cardiovascular …, 2022 - frontiersin.org
Objective: To systematically review the efficacy and safety of sacubitril-valsartan in the
treatment of acute myocardial infarction complicated with heart failure and to observe …

Effects of sacubitril/valsartan on ventricular remodeling in patents with left ventricular systolic dysfunction following acute anterior wall myocardial infarction

H Wang, X Fu - Coronary artery disease, 2021 - journals.lww.com
Objective The aim of this study was to investigate the effect of sacubitril/valsartan (Sal/Val)
on left ventricular (LV) remodeling in patients with LV systolic dysfunction following acute …

The impact of a dose of the angiotensin receptor blocker valsartan on post‐myocardial infarction ventricular remodelling

K Park, YD Kim, KS Kim, SH Lee, TH Park… - ESC Heart …, 2018 - Wiley Online Library
Aims Although clinical guidelines advocate the use of the highest tolerated dose of
angiotensin‐converting enzyme inhibitors or angiotensin receptor blockers after acute …

Sacubitril/valsartan averts adverse post-infarction ventricular remodeling and preserves systolic function in rabbits

J Torrado, C Cain, AG Mauro, F Romeo… - Journal of the American …, 2018 - jacc.org
Abstract Background: Sacubitril/valsartan (SAC/VAL) is approved by the US Food and Drug
Administration for heart failure with reduced ejection fraction (HFrEF). Objectives: This study …