Objective To evaluate the prognostic value and explore the biological significance of gap
junction protein beta 2 (GJB2 or Cx26) in cervical cancer (CC). Methods We first compared …

Background: A wide range of connexins are situated between normal-normal cells, cancer-
cancer cells, and cancer-normal cells. Abnormalities in connexin expression are typically …

Gap Junction Protein Alpha 1 (GJA1) belongs to the gap junction family and has been
widely studied in cancers. We evaluated the role of GJA1 in cervical cancer (CC) using …

Background GJB2 plays an essential role in the growth and progression of several cancers.
However, asystematic pan-cancer analysis of GJB2 is lacking. Therefore, in this study, we …

Gap junction β‑2 gene (GJB2, also known as connexin 26) is a member of the connexin
family which forms gap junction channels. Many connexin genes have been considered to …

The role of connexin proteins (Cx), which form gap junctions (GJ), in progression and
chemotherapeutic sensitivity of cervical cancer (CaCx), is unclear. Using cervix specimens …

Background Gap junction beta-4 protein (GJB4), or connexin 30.3, a member of integral
membrane proteins, has been shown to involve and may function as a tumor promoter in …

Gap juctions are transmembrane communication channels known to be involved in the
control of cell proliferation by mediating the exchange of ions and small molecules between …

The poor prognosis of head and neck squamous cell carcinoma (HNSCC) is partly due to
the lack of reliable predictive markers. Connexin 43 (Cx43) protein and its cell …

Most lung cancer patients are diagnosed late with metastasis, which is the major cause of
cancer-related death and recurrent tumors that often exhibit chemoresistance. In the present …