Nurturing the early life gut microbiome and immune maturation for long term health

SK Dogra, CK Chung, D Wang, O Sakwinska… - Microorganisms, 2021 - mdpi.com
Early life is characterized by developmental milestones such as holding up the head, turning
over, sitting up and walking that are typically achieved sequentially in specific time windows …

A good start in life is important—perinatal factors dictate early microbiota development and longer term maturation

S Wang, M Egan, CA Ryan, P Boyaval… - FEMS microbiology …, 2020 - academic.oup.com
Maternal health status is vital for the development of the offspring of humans, including
physiological health and psychological functions. The complex and diverse microbial …

Temporal development of the infant gut microbiome

RE Moore, SD Townsend - Open biology, 2019 - royalsocietypublishing.org
The majority of organisms that inhabit the human body reside in the gut. Since babies are
born with an immature immune system, they depend on a highly synchronized microbial …

Early‐life gut microbiome—the importance of maternal and infant factors in its establishment

FR Kapourchali, GAM Cresci - Nutrition in Clinical Practice, 2020 - Wiley Online Library
The early‐life microbiome is gaining appreciation as a major influencer in human
development and long‐term health. Multiple factors are known to influence the initial …

Divergent maturational patterns of the infant bacterial and fungal gut microbiome in the first year of life are associated with inter-kingdom community dynamics and …

EM Mercer, HR Ramay, S Moossavi… - Microbiome, 2024 - Springer
Background The gut microbiome undergoes primary ecological succession over the course
of early life before achieving ecosystem stability around 3 years of age. These maturational …

The human microbiome and child growth–first 1000 days and beyond

RC Robertson, AR Manges, BB Finlay… - Trends in …, 2019 - cell.com
The assembly of microbial communities within the gastrointestinal tract during early life plays
a critical role in immune, endocrine, metabolic, and other host developmental pathways …

Gut microbial functional maturation and succession during human early life

T Cerdó, A Ruiz, I Acuña, R Jáuregui… - Environmental …, 2018 - Wiley Online Library
The evolutional trajectory of gut microbial colonization from birth has been shown to prime
for health later in life. Here, we combined cultivation‐independent 16S rRNA gene …

Early life colonization of the human gut: microbes matter everywhere

K Korpela, WM de Vos - Current opinion in microbiology, 2018 - Elsevier
Highlights•The intestinal microbiota follows a common successional pattern in early
life.•Particular bacterial taxa are mainly transmitted from the mother to the infant after …

The intestinal microbiome in early life: health and disease

MC Arrieta, LT Stiemsma, N Amenyogbe… - Frontiers in …, 2014 - frontiersin.org
Human microbial colonization begins at birth and continues to develop and modulate in
species abundance for about 3 years, until the microbiota becomes adult-like. During the …

[HTML][HTML] Factors influencing development of the infant microbiota: From prenatal period to early infancy

S Jeong - Clinical and Experimental Pediatrics, 2022 - ncbi.nlm.nih.gov
During early life, the gut microbial composition rapidly changes by maternal microbiota
composition, delivery mode, infant feeding mode, antibiotic usage, and various …