Maternal diabetes has been widely reported to adversely affect oocyte quality. Although
various molecules and pathways may be involved in this process, strategies to prevent …

In mammalian ovaries, oocytes are physically coupled to somatic granulosa cells, and this
coupling is crucial for the growth and development of competent oocytes as it mediates the …

Aims Previous reports have demonstrated that melatonin exists in multiple extrapineal sites,
and higher amounts of melatonin are present in human follicular fluid than in serum, which …

With increase in women's age, the reproductive capability of female mammals decreases
dramatically caused by age-related oxidative stress, coinciding with the decline in the …

Maternal obesity in humans is associated with poor outcomes across the reproductive
spectrum. Emerging evidence indicates that these defects are likely attributed to factors …

Cadmium (Cd) is one major environmental pollutant that can cause detrimental impacts on
human as well as animal reproductive systems as a result of oxidative stress. It is widely …

Melatonin (MT) can improve the effect of cryopreservation on oocytes by suppressing
oxidative stress and maintaining the permeability of the oolemma. In this study, MT was …

Melatonin (MT) regulates reproductive performance as a potent antioxidant; however, its
beneficial effects on oocyte development remain largely unknown, especially in human …

The physiology of oocyte in vitro maturation remains elusive. Generally, the oocytes have a
very low maturation rate under in vitro conditions. In the current study, we found that …

Melatonin is a well‐characterized antioxidant that has been successfully used to protect
oocytes from reactive oxygen species during in vitro maturation (IVM), resulting in improved …