Calcium Channels as a Potential Therapeutic Target for Alzheimer's Disease

P Sharma, P Thapak, B Chandwani, H Kharkwal… - … Drug Targets for …, 2023 - Springer
Alzheimer's disease (AD) is the most common type of dementia that characterizes the
accumulation of amyloid-β plaques and neurofibrillary tangles in the brain. AD is the most …

[HTML][HTML] Role of calcium modulation in the pathophysiology and treatment of Alzheimer's disease

D Baracaldo-Santamaría, SS Avendaño-Lopez… - International journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) is a chronic neurodegenerative disease and the most frequent
cause of progressive dementia in senior adults. It is characterized by memory loss and …

[HTML][HTML] Calcium dyshomeostasis in Alzheimer's disease pathogenesis

R Cascella, C Cecchi - International journal of molecular sciences, 2021 - mdpi.com
Alzheimer's disease (AD) is the most common age-related neurodegenerative disorder that
is characterized by amyloid β-protein deposition in senile plaques, neurofibrillary tangles …

[HTML][HTML] Calcium signalling in Alzheimer's disease: From pathophysiological regulation to therapeutic approaches

M Chami - Cells, 2021 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative pathology representing a socioeconomic
challenge, however, the complex mechanism behind the disease is not yet fully understood …

[HTML][HTML] Calcium signaling in Alzheimer's disease & therapies

BCK Tong, AJ Wu, M Li, KH Cheung - Biochimica et Biophysica Acta (BBA) …, 2018 - Elsevier
Alzheimer's disease (AD) is the most common type of dementia and is characterized by the
accumulation of amyloid (Aβ) plaques and neurofibrillary tangles in the brain. Much attention …

Calcium dysregulation in Alzheimer's disease: from mechanisms to therapeutic opportunities

JT Yu, RCC Chang, L Tan - Progress in neurobiology, 2009 - Elsevier
Calcium is involved in many facets of neuronal physiology, including activity, growth and
differentiation, synaptic plasticity, and learning and memory, as well as pathophysiology …

Role of calcium dysregulation in Alzheimer's disease and its therapeutic implications

M Joshi, S Joshi, M Khambete… - Chemical Biology & …, 2023 - Wiley Online Library
The increasing incidence of Alzheimer's disease (AD) coupled with the lack of therapeutics
to address the underlying pathology of the disease has necessitated the need for exploring …

Intracellular calcium dysregulation: implications for Alzheimer's disease

S Magi, P Castaldo, ML Macrì… - BioMed research …, 2016 - Wiley Online Library
Alzheimer's Disease (AD) is a neurodegenerative disorder characterized by progressive
neuronal loss. AD is associated with aberrant processing of the amyloid precursor protein …

Calcium dysregulation in Alzheimer's disease

L Bojarski, J Herms, J Kuznicki - Neurochemistry international, 2008 - Elsevier
Alzheimer disease (AD) is the most common form of adult dementia. Its pathological
hallmarks are synaptic degeneration, deposition of amyloid plaques and neurofibrillary …

[HTML][HTML] Calcium dysregulation in Alzheimer's disease: a target for new drug development

Y Wang, Y Shi, H Wei - Journal of Alzheimer's disease & …, 2017 - ncbi.nlm.nih.gov
Alzheimer's disease (AD) is a devastating neurodegenerative disorder and the most
common cause of dementia among aged people whose population is rapidly increasing. AD …