Immune responses following locoregional treatment for hepatocellular carcinoma: possible roles of adjuvant immunotherapy

JW Han, SK Yoon - Pharmaceutics, 2021 - mdpi.com
Hepatocellular carcinoma (HCC) is a common cause of cancer-related deaths worldwide.
Unlike other types of cancer, HCC can be treated with locoregional treatments (LRTs) such …

The immune modulation effect of locoregional therapies and its potential synergy with immunotherapy in hepatocellular carcinoma

P Singh, S Toom, A Avula, V Kumar… - Journal of …, 2020 - Taylor & Francis
Locoregional therapies (LRTs) including radiofrequency ablation, surgical resection, and
TACE, play a pivotal role in the treatment of early stage/locally advanced hepatocellular …

The immune response of hepatocellular carcinoma after locoregional and systemic therapies: The available combination option for immunotherapy

Y Duan, H Zhang, T Tan, W Ye, K Yin, Y Yu… - BioScience …, 2023 - jstage.jst.go.jp
Hepatocellular carcinoma (HCC) is associated with a highly heterogeneous immune
environment that produces an immune response to various locoregional treatments (LRTs) …

Retrospective analysis of the immunogenic effects of intra-arterial locoregional therapies in hepatocellular carcinoma: a rationale for combining selective internal …

L Craciun, R de Wind, P Demetter, V Lucidi, A Bohlok… - BMC cancer, 2020 - Springer
Background Immunotherapy represents a promising option for treatment of hepatocellular
carcinoma (HCC) in cirrhotic patients but its efficacy is currently inconsistent and …

[HTML][HTML] Current status and perspectives of immune-based therapies for hepatocellular carcinoma

M Aerts, D Benteyn, H Van Vlierberghe… - World Journal of …, 2016 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is a frequent cancer with a high mortality. For early stage
cancer there are potentially curative treatments including local ablation, resection and liver …

The synergistic effect of interventional locoregional treatments and immunotherapy for the treatment of hepatocellular carcinoma

N Brandi, M Renzulli - International Journal of Molecular Sciences, 2023 - mdpi.com
Immunotherapy has remarkably revolutionized the management of advanced HCC and
prompted clinical trials, with therapeutic agents being used to selectively target immune cells …

Immunomodulation for hepatocellular carcinoma therapy: current challenges

ZM Jilkova, J Ghelfi, T Decaens - Current Opinion in Oncology, 2022 - journals.lww.com
Immunomodulation for hepatocellular carcinoma therapy: curre... : Current Opinion in Oncology
Immunomodulation for hepatocellular carcinoma therapy: current challenges : Current Opinion …

[HTML][HTML] Combination approaches in hepatocellular carcinoma: how systemic treatment can benefit candidates to locoregional modalities

LG da Fonseca, RLC Araujo - World Journal of Gastroenterology, 2022 - ncbi.nlm.nih.gov
The management of hepatocellular carcinoma (HCC) is challenging because most patients
have underlying cirrhosis, and the treatment provides, historically, a limited impact on the …

[HTML][HTML] Management and treatment of hepatocellular carcinoma with immunotherapy: a review of current and future options

S Ghavimi, T Apfel, H Azimi, A Persaud… - Journal of Clinical …, 2020 - ncbi.nlm.nih.gov
With mortality rates of liver cancer doubling in the last 20 years, this disease is on the rise
and has become the fifth most common cancer in men and the seventh most common …

Combination of ablation and immunotherapy for hepatocellular carcinoma: where we are and where to go

K Wang, C Wang, H Jiang, Y Zhang, W Lin… - Frontiers in …, 2021 - frontiersin.org
Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths
worldwide and is increasing in incidence. Local ablative therapy plays a leading role in HCC …