Improved photodynamic therapy efficacy of protoporphyrin IX-loaded polymeric micelles using erlotinib pretreatment

L Yan, J Miller, M Yuan, JF Liu, TM Busch… - …, 2017 - ACS Publications
Photodynamic therapy (PDT) has attracted widespread attention in recent years as a
noninvasive and highly selective approach for cancer treatment. We have previously …

Multicompartment Micelles with Adjustable Poly(ethylene glycol) Shell for Efficient in Vivo Photodynamic Therapy

CV Synatschke, T Nomoto, H Cabral, M Fortsch… - ACS …, 2014 - ACS Publications
We describe the preparation of well-defined multicompartment micelles from polybutadiene-
block-poly (1-methyl-2-vinyl pyridinium methyl sulfate)-block-poly (methacrylic …

Ultrasensitive redox-responsive porphyrin-based polymeric nanoparticles for enhanced photodynamic therapy

Y Xue, J Tian, L Xu, Z Liu, Y Shen, W Zhang - European Polymer Journal, 2019 - Elsevier
Stimulus-sensitive nanoparticles (NPs) have been established to widely adapt to remarkable
abnormalities under the tumor microenvironment, which can observably enhance the …

Diblock copolymer micelles deliver hydrophobic protoporphyrin IX for photodynamic therapy

B Li, EH Moriyama, F Li, MT Jarvi… - Photochemistry and …, 2007 - Wiley Online Library
Polymeric micelles are emerging as an effective drug delivery system for hydrophobic
photosensitizers in photodynamic therapy (PDT). The objective of this study was to …

[HTML][HTML] Core–shell poly-methyl methacrylate nanoparticles covalently functionalized with a non-symmetric porphyrin for anticancer photodynamic therapy

M Ballestri, E Caruso, A Guerrini, C Ferroni… - … of Photochemistry and …, 2018 - Elsevier
Photodynamic therapy (PDT) is an anticancer modality that exploits singlet oxygen and other
reactive oxygen species, that are formed by selective irradiation of photosensitive …

Pluronic® mixed micelles as efficient nanocarriers for benzoporphyrin derivatives applied to photodynamic therapy in cancer cells

DS Pellosi, AL Tessaro, F Moret, E Gaio… - … of Photochemistry and …, 2016 - Elsevier
In this study we attempted to develop Pluronic micelles delivering the photodynamic therapy
photosensitizers benzoporphyrin derivatives (BPD). The BPD A-ring (BPDMA or …

Nanoscopic micelle delivery improves the photophysical properties and efficacy of photodynamic therapy of protoporphyrin IX

H Ding, BD Sumer, CW Kessinger, Y Dong… - Journal of Controlled …, 2011 - Elsevier
Nanodelivery systems have shown considerable promise in increasing the solubility and
delivery efficiency of hydrophobic photosensitizers for photodynamic therapy (PDT) …

Efficient anti-tumor effect of photodynamic treatment with polymeric nanoparticles composed of polyethylene glycol and polylactic acid block copolymer encapsulating …

K Ogawara, T Shiraishi, T Araki, T Watanabe… - European Journal of …, 2016 - Elsevier
To develop potent and safer formulation of photosensitizer for cancer photodynamic therapy
(PDT), we tried to formulate hydrophobic porphyrin derivative, photoprotoporphyrin IX …

Photoactivation switch from type II to type I reactions by electron-rich micelles for improved photodynamic therapy of cancer cells under hypoxia

H Ding, H Yu, Y Dong, R Tian, G Huang… - Journal of Controlled …, 2011 - Elsevier
Photodynamic therapy (PDT) is an emerging clinical modality for the treatment of a variety of
diseases. Most photosensitizers are hydrophobic and poorly soluble in water. Many new …

[HTML][HTML] Synthesis and Biological Properties of EGFR-Targeted Photosensitizer Based on Cationic Porphyrin

YS Bortnevskaya, NA Shiryaev, NS Zakharov… - Pharmaceutics, 2023 - mdpi.com
Photodynamic therapy (PDT) in oncology is characterized by low invasiveness, minimal side
effects, and little tissue scarring. Increasing the selectivity of PDT agents toward a cellular …