The role of BMI1 in endometrial cancer and other cancers

Y Zhao, W Yang, K Zheng, J Chen, X Jin - Gene, 2023 - Elsevier
Endometrial cancer (EC) is the third leading gynecological malignancy, and its treatment
remains challenging. B cell-specific Moloney murine leukemia virus integration site-1 (BMI1) …

BMI‑1 promotes invasion and metastasis in endometrial adenocarcinoma and is a poor prognostic factor Corrigendum in/10.3892/or. 2022.8352

J Yu, L Chen, Z Bao, Y Liu, G Liu… - Oncology …, 2020 - spandidos-publications.com
Endometrial adenocarcinoma is one of the most common types of gynecological
malignancies and its incidence and mortality rates are increasing. Due to tumor recurrence …

Inhibition of BMI1, a therapeutic approach in endometrial cancer

M Buechel, A Dey, SKD Dwivedi, A Crim, K Ding… - Molecular cancer …, 2018 - AACR
With rising incidence rates, endometrial cancer is one of the most common gynecologic
malignancies in the United States. Although surgery provides significant survival benefit to …

Enhancing chemotherapy response with Bmi-1 silencing in ovarian cancer

E Wang, S Bhattacharyya, A Szabolcs… - PloS one, 2011 - journals.plos.org
Undoubtedly ovarian cancer is a vexing, incurable disease for patients with recurrent cancer
and therapeutic options are limited. Although the polycomb group gene, Bmi-1 that regulates …

The mechanism of BMI1 in regulating cancer stemness maintenance, metastasis, chemo-and radiation resistance

X Xu, Z Wang, N Liu, P Zhang, H Liu… - Cancer Translational …, 2018 - search.proquest.com
BMI1 is involved in the occurrence and development of many types of cancer through a
variety of signaling pathways. BMI1, which is overexpressed in cancer, is often associated …

Overexpression of Bmi-1 in uterine cervical cancer: correlation with clinicopathology and prognosis

X Zhang, CX Wang, C Zhu, J Zhang, S Kan… - International Journal of …, 2010 - ijgc.bmj.com
Introduction: B-cell-specific Moloney murine leukemia virus integration site 1 (Bmi-1) is a
member of polycomb group, which participates in axial patterning, hematopoiesis, cell cycle …

Role of BMI1 in epithelial ovarian cancer: investigated via the CRISPR/Cas9 system and RNA sequencing

Q Zhao, Q Qian, D Cao, J Yang, T Gui… - Journal of Ovarian …, 2018 - Springer
Background B-cell-specific Moloney murine leukemia virus integration site 1 (BMI1) might be
an appropriate biomarker in the management of epithelial ovarian cancer (EOC). However …

[HTML][HTML] Silencing Bmi1 expression suppresses cancer stemness and enhances chemosensitivity in endometrial cancer cells

M Kim, S Lee, WH Park, DH Suh, K Kim, YB Kim… - Biomedicine & …, 2018 - Elsevier
Background Bmi1, a polycomb group gene, is essential for self-renewal of stem cells and is
frequently upregulated in various cancer cells. We aimed to investigate the effect of Bmi1 …

Downregulated miR-495 inhibits the G1-S phase transition by targeting bmi-1 in breast cancer

L Wang, JL Liu, L Yu, XX Liu, HM Wu, FY Lei, S Wu… - Medicine, 2015 - journals.lww.com
Abstract Bmi-1 (B cell-specific Moloney murine leukemia virus integration site 1) is
upregulated in breast cancer and was involved in many malignant progressions of breast …

BMI-1 promotes self-renewal of radio-and temozolomide (TMZ)-resistant breast cancer cells

Y Yan, Y Wang, P Zhao, W Ma, Z Hu… - Reproductive …, 2017 - journals.sagepub.com
Breast cancer is a hormone-dependent malignancy and is the most prevalent cause of
cancer-related mortality among females. Radiation therapy and chemotherapy are common …