[HTML][HTML] Local delivery and glioblastoma: why not combining sustained release and targeting?

C Gazaille, M Sicot, P Saulnier, J Eyer… - Frontiers in Medical …, 2021 - frontiersin.org
Glioblastoma is one of the most aggressive brain tumors and is associated with a very low
overall median survival despite the current treatment. The standard of care used in clinic is …

[HTML][HTML] Injectable local drug delivery systems for glioblastoma: a systematic review and meta-analysis of progress to date

Y Wang, C Bastiancich, B Newland - Biomaterials Science, 2023 - pubs.rsc.org
Glioblastoma (GBM) is an aggressive malignant cancer associated with bleak prognosis and
high mortality. The current standard of care for GBM is maximum surgical resection plus …

Rationally designed drug delivery systems for the local treatment of resected glioblastoma

C Bastiancich, A Malfanti, V Préat, R Rahman - Advanced drug delivery …, 2021 - Elsevier
Glioblastoma (GBM) is a particularly aggressive brain cancer associated with high
recurrence and poor prognosis. The standard of care, surgical resection followed by …

Current status of local therapy in malignant gliomas—a clinical review of three selected approaches

TA Juratli, G Schackert, D Krex - Pharmacology & therapeutics, 2013 - Elsevier
Malignant gliomas are the most frequently occurring, devastating primary brain tumors, and
are coupled with a poor survival rate. Despite the fact that complete neurosurgical resection …

Delivery of local therapeutics to the brain: working toward advancing treatment for malignant gliomas

KL Chaichana, L Pinheiro, H Brem - Therapeutic delivery, 2015 - Taylor & Francis
Malignant gliomas, including glioblastoma and anaplastic astrocytomas, are characterized
by their propensity to invade surrounding brain parenchyma, making curative resection …

Localized drug delivery systems in high‐grade glioma therapy—from construction to application

M Hauck, D Hellmold, C Kubelt… - Advanced …, 2022 - Wiley Online Library
High‐grade gliomas are the most common and most malign primary brain tumors. Current
therapy approaches only reach unsatisfactory results, still not providing a long‐lasting time …

[HTML][HTML] Local delivery to malignant brain tumors: Potential biomaterial-based therapeutic/adjuvant strategies

M Alghamdi, M Gumbleton, B Newland - Biomaterials Science, 2021 - pubs.rsc.org
Glioblastoma (GBM) is the most aggressive malignant brain tumor and is associated with a
very poor prognosis. The standard treatment for newly diagnosed patients involves total …

Advances in drug delivery technology for the treatment of glioblastoma multiforme

GD Cha, T Kang, S Baik, D Kim, SH Choi… - Journal of Controlled …, 2020 - Elsevier
Glioblastoma multiforme (GBM) is a particularly aggressive and malignant type of brain
tumor, notorious for its high recurrence rate and low survival rate. The treatment of GBM is …

Recent advances in targeted drug delivery for the treatment of glioblastoma

M Mao, Y Wu, Q He - Nanoscale, 2024 - pubs.rsc.org
Glioblastoma multiforme (GBM) is one of the highly malignant brain tumors characterized by
significant morbidity and mortality. Despite the recent advancements in the treatment of …

[HTML][HTML] Local drug delivery strategies for glioblastoma treatment

GD Cha, S Jung, SH Choi… - Brain Tumor Research …, 2022 - synapse.koreamed.org
Glioblastoma multiforme (GBM) is a brain tumor notorious for its malignancy. The key reason
for the limited efficacy of standard treatment is the high recurrence rate of GBM, even after …