Concurrent cetuximab and nivolumab as a second-line or beyond treatment of patients with recurrent and/or metastatic head and neck squamous cell carcinoma …

CH Chung, M Bonomi, CE Steuer, J Li, P Bhateja… - Cancers, 2021 - mdpi.com
Simple Summary To improve overall survival (OS), we evaluated a combination of
cetuximab and nivolumab for toxicity and efficacy in patients with incurable recurrent and/or …

Phase II multi-institutional clinical trial result of concurrent cetuximab and nivolumab in recurrent and/or metastatic head and neck squamous cell carcinoma

CH Chung, J Li, CE Steuer, P Bhateja, M Johnson… - Clinical Cancer …, 2022 - AACR
Purpose: A phase II multi-institutional clinical trial was conducted to determine overall
survival (OS) in patients with recurrent and/or metastatic (R/M) head and neck squamous …

Nivolumab in patients with recurrent or metastatic squamous cell carcinoma of the head and neck: efficacy and safety in CheckMate 141 by prior cetuximab use

RL Ferris, L Licitra, J Fayette, C Even… - Clinical Cancer …, 2019 - AACR
Purpose: Cetuximab, which modulates immune responses, may affect the efficacy of
subsequent immunotherapy. Here, we assessed outcomes with nivolumab, by prior …

Nivolumab plus ipilimumab versus EXTREME regimen as first-line treatment for recurrent/metastatic squamous cell carcinoma of the head and neck: the final results of …

RI Haddad, K Harrington, M Tahara… - Journal of Clinical …, 2023 - ascopubs.org
PURPOSE CheckMate 651 (ClinicalTrials. gov identifier: NCT02741570) evaluated first-line
nivolumab plus ipilimumab versus EXTREME (cetuximab plus cisplatin/carboplatin plus …

Pembrolizumab plus cetuximab in patients with recurrent or metastatic head and neck squamous cell carcinoma: an open-label, multi-arm, non-randomised …

AG Sacco, R Chen, FP Worden, DJL Wong… - The Lancet …, 2021 - thelancet.com
Summary Background Pembrolizumab (PD-1 inhibitor) and cetuximab (EGFR inhibitor) are
active as single agents and in combination with cytotoxic chemotherapy for recurrent or …

Both combined or sequential use with immune checkpoint inhibitors on cetuximab-treated patients with recurrent or metastatic head and neck squamous cell …

MY Lien, TH Wang, CY Hsieh, MH Tsai, CH Hua… - Oral Oncology, 2021 - Elsevier
Background After the introduction of ICI treatment, data about feasibility and activity of a
cetuximab-containing first-line therapy in patients with recurrent and/or metastatic head and …

Pembrolizumab with or without chemotherapy in recurrent or metastatic head and neck squamous cell carcinoma: updated results of the phase III KEYNOTE-048 study

KJ Harrington, B Burtness, R Greil… - Journal of Clinical …, 2023 - ascopubs.org
PURPOSE Pembrolizumab and pembrolizumab-chemotherapy demonstrated efficacy in
recurrent/metastatic head and neck squamous cell carcinoma in KEYNOTE-048. Post hoc …

How standard is second-line cetuximab in recurrent or metastatic head and neck cancer in 2017?

P Szturz, TY Seiwert, JB Vermorken - Journal of Clinical Oncology …, 2017 - europepmc.org
How Standard Is Second-Line Cetuximab in Recurrent or Metastatic Head and Neck Cancer in
2017? - Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe PMC Menu …

Optimizing treatments for recurrent or metastatic head and neck squamous cell carcinoma

P Specenier, JB Vermorken - Expert Review of Anticancer Therapy, 2018 - Taylor & Francis
Introduction: The majority of patients with locally advanced head and neck squamous cell
carcinoma (HNSCC) will recur. The treatment of patients with recurrent/metastatic (R/M …

Paradigm change in first-line treatment of recurrent and/or metastatic head and neck squamous cell carcinoma

E Borcoman, G Marret, C Le Tourneau - Cancers, 2021 - mdpi.com
Simple Summary Immunotherapy has made a breakthrough in the treatment of patients with
recurrent and/or metastatic head and neck squamous cell carcinoma in the second line …