A series of phenoxyalkyl and phenylthioalkyl amides were prepared as melatoninergic
ligands. Modulation of affinity of the newly synthesized compound by applying SARs around …

A series of substituted N-[3-(3-methoxyphenyl) propyl] amides were synthesized and their
binding affinities towards human melatonin MT1 and MT2 receptors were evaluated. It was …

Following our studies of the melatoninergic receptors, we have developed new
tetrahydronaphthalenic derivatives of melatonin that have been tested as selective …

A series of N-(2-phenylbenzofuran-3-yl) ethyl amide and N-(2-arylalkylbenzofuran-3-yl) ethyl
amide derivatives were synthesized and evaluated as melatonin receptor ligands. The …

A series of naphthalenic analogues of melatonin were prepared and evaluated as melatonin
receptor MT2 selective ligands. Activity and MT2 selectivity can be modulated with suitable …

Two novel series of melatonin-derived compounds have been synthesized and
pharmacologically evaluated at the MT1 and MT2 subtypes of melatonin receptors …

Tetrahydronaphthalenic analogues of melatonin have been synthesized and evaluated as
melatonin receptor ligands. Introduction of a phenyl substituent in the 3-position of the …

A novel series of melatonin receptor ligands, characterized by a N-(substituted-anilinoethyl)
amido scaffold, along with preliminary structure–activity relationships (SARs), is presented …

A novel series of melatonin receptor ligands was discovered by opening the cyclic scaffolds
of known classes of high affinity melatonin receptor antagonists, while retaining the …

A new series of melatonin (MLT) dimers were obtained by linking together two melatonin
units with a linear alkyl chain through the MLT acetamido group or through a C-2 …