A Comprehensive Exploration of Bioluminescence Systems, Mechanisms, and Advanced Assays for Versatile Applications

AN Dunuweera, SP Dunuweera… - Biochemistry …, 2024 - Wiley Online Library
Bioluminescence has been a fascinating natural phenomenon of light emission from living
creatures. It happens when the enzyme luciferase facilitates the oxidation of luciferin …

[HTML][HTML] Applications of bioluminescence in biotechnology and beyond

AJ Syed, JC Anderson - Chemical Society Reviews, 2021 - pubs.rsc.org
Bioluminescence is the fascinating natural phenomenon by which living creatures produce
light. Bioluminescence occurs when the oxidation of a small-molecule luciferin is catalysed …

Standardization of luminescence, fluorescence measurements, and light microscopy: Current situation and perspectives

A Sasaki, Y Ohmiya - Biophysics and Physicobiology, 2022 - jstage.jst.go.jp
Improving reproducibility and confidence are important challenges in biomedical
measurements, such as luminescence and fluorescence measurements [1]. In general …

1001 lights: luciferins, luciferases, their mechanisms of action and applications in chemical analysis, biology and medicine

ZM Kaskova, AS Tsarkova, IV Yampolsky - Chemical Society Reviews, 2016 - pubs.rsc.org
Bioluminescence (BL) is a spectacular phenomenon involving light emission by live
organisms. It is caused by the oxidation of a small organic molecule, luciferin, with molecular …

Current advanced bioluminescence technology in drug discovery

H Hoshino - Expert Opinion on Drug Discovery, 2009 - Taylor & Francis
Background: Bioluminescence technology is based on the luciferin–luciferase reaction and
is generally well known as a reporter gene assay system that uses firefly luciferase. It has …

[HTML][HTML] Bioluminescent Systems for Theranostic Applications

H Kim, SO Jung, S Lee, Y Lee - International Journal of Molecular …, 2024 - mdpi.com
Bioluminescence, the light produced by biochemical reactions involving luciferases in living
organisms, has been extensively investigated for various applications. It has attracted …

Advances in luminescence-based technologies for drug discovery

B Baljinnyam, M Ronzetti… - Expert opinion on drug …, 2023 - Taylor & Francis
Introduction Luminescence-based technologies, specifically bioluminescence and
chemiluminescence, are powerful tools with extensive use in drug discovery. Production of …

Advances in bioluminescence imaging: new probes from old recipes

Z Yao, BS Zhang, JA Prescher - Current opinion in chemical biology, 2018 - Elsevier
Highlights•Advances in bioluminescent tool production that mirror trends in fluorescent
probe development.•New bioluminescent platforms based on naturally occurring luciferases …

[HTML][HTML] Seeing (and using) the light: recent developments in bioluminescence technology

AC Love, JA Prescher - Cell Chemical Biology, 2020 - cell.com
Bioluminescence has long been used to image biological processes in vivo. This technology
features luciferase enzymes and luciferin small molecules that produce visible light …

Activity‐Based Luciferase‐Luciferin Bioluminescence System for Bioimaging Applications

T Xia, X Cheng, W Zhan, G Liang - Analysis & Sensing, 2021 - Wiley Online Library
There is growing interest in applying bioluminescence for imaging varies biological
processes in life sciences due to its high resolution, selectivity, and signal/noise ratio (no …