[HTML][HTML] Aberrant post-transcriptional regulation of protein expression in the development of chronic obstructive pulmonary disease

N Aloufi, A Alluli, DH Eidelman, CJ Baglole - International Journal of …, 2021 - mdpi.com
Chronic obstructive pulmonary disease (COPD) is an incurable and prevalent respiratory
disorder that is characterized by chronic inflammation and emphysema. COPD is primarily …

Non-coding RNAs in the pathogenesis of COPD

EG De Smet, P Mestdagh, J Vandesompele… - Thorax, 2015 - thorax.bmj.com
A large part of the human genome is transcribed in non-coding RNAs, transcripts that do not
code for protein, including microRNAs (miRNAs) and long non-coding RNAs (lncRNAs) …

The roles of microRNAs in the pathogenesis of chronic obstructive pulmonary disease

X Huang, Z Zhu, X Guo, X Kong - International immunopharmacology, 2019 - Elsevier
Chronic obstructive pulmonary disease (COPD) is characterized by a progressive and
irreversible airflow obstruction, with an abnormal lung function. The etiology of COPD …

Long noncoding transcriptome in chronic obstructive pulmonary disease

D Devadoss, C Long, RJ Langley… - American journal of …, 2019 - atsjournals.org
Chronic airway inflammation from recurring exposures to noxious environmental stimuli
results in a progressive and irreversible airflow limitation and the lung parenchymal damage …

[HTML][HTML] Role of non-coding RNAs in post-transcriptional regulation of lung diseases

DK Soni, R Biswas - Frontiers in Genetics, 2021 - frontiersin.org
Non-coding RNAs (ncRNAs), notably microRNAs (miRNAs) and long noncoding RNAs
(lncRNAs), have recently gained increasing consideration because of their versatile role as …

[HTML][HTML] Systematic analysis of various RNA transcripts and construction of biological regulatory networks at the post-transcriptional level for chronic obstructive …

B Li, J Zhang, H Dong, X Feng, L Yu, J Zhu… - Journal of Translational …, 2023 - Springer
Background Although chronic inflammation, oxidative stress, airway remodeling, and
protease-antiprotease imbalance have been implicated in chronic obstructive pulmonary …

Comprehensive analysis of miRNA-mRNA-lncRNA networks in non-smoking and smoking patients with chronic obstructive pulmonary disease

Y Qian, Z Mao, Y Shi, Z Liu, Q Cao… - Cellular Physiology and …, 2018 - karger.com
Abstract Background/Aims: Chronic obstructive pulmonary disease (COPD) is a major cause
of morbidity and mortality worldwide. This study aimed to identify overlapping or diverging …

RNA-binding proteins as a molecular link between COPD and lung cancer

I Salvato, L Ricciardi, F Nucera, A Nigro… - COPD: Journal of …, 2023 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) represents an independent risk factor for
lung cancer development. Accelerated cell senescence, induced by oxidative stress and …

Investigation of molecular mechanisms underlying immunological and respiratory disorders using single-cell RNA sequencing

CT Wohnhaas - 2022 - kops.uni-konstanz.de
Respiratory diseases are a leading cause of disability and death worldwide. Several of the
most prevalent respiratory diseases are associated with smoking, including chronic …

[HTML][HTML] Noncoding RNAs in Chronic Obstructive Pulmonary Disease: From Pathogenesis to Therapeutic Targets

B Ren, H Su, C Bao, H Xu, Y Xiao - Non-coding RNA Research, 2024 - Elsevier
Chronic obstructive pulmonary disease (COPD) is the most prevalent chronic respiratory
disorder that is becoming the leading cause of morbidity and mortality on a global scale …