Mechanisms of acute lung injury/acute respiratory distress syndrome

BT Suratt, PE Parsons - Clinics in chest medicine, 2006 - chestmed.theclinics.com
In the 4 decades that have elapsed since Ashbaugh and colleagues [1] first described acute
lung injury/acute respiratory distress syndrome (ALI/ARDS), tremendous strides have been …

[HTML][HTML] Redefining ARDS: a paradigm shift

J Villar, T Szakmany, G Grasselli, L Camporota - Critical Care, 2023 - Springer
Although the defining elements of “acute respiratory distress syndrome”(ARDS) have been
known for over a century, the syndrome was first described in 1967. Since then, despite …

[HTML][HTML] Advancing precision medicine for the diagnosis and treatment of acute respiratory distress syndrome

AN Rizzo, NR Aggarwal, BT Thompson… - Journal of Clinical …, 2023 - mdpi.com
Acute respiratory distress syndrome (ARDS) is a common and life-threatening cause of
respiratory failure. Despite decades of research, there are no effective pharmacologic …

[HTML][HTML] Pharmacological treatments in ARDS; a state-of-the-art update

AJ Boyle, RM Sweeney, DF McAuley - BMC medicine, 2013 - Springer
Despite its high incidence and devastating outcomes, acute respiratory distress syndrome
(ARDS) has no specific treatment, with effective therapy currently limited to minimizing …

What is the acute respiratory distress syndrome?

J Villar - Respiratory care, 2011 - rc.rcjournal.com
It has been known for decades that shock and sepsis can cause a syndrome of acute
respiratory failure with characteristics of non-cardiogenic pulmonary edema. Over the years …

New insights into clinical and mechanistic heterogeneity of the acute respiratory distress syndrome: summary of the Aspen Lung Conference 2021

TR Martin, RL Zemans, LB Ware… - American journal of …, 2022 - atsjournals.org
Clinical and molecular heterogeneity are common features of human disease.
Understanding the basis for heterogeneity has led to major advances in therapy for many …

[PDF][PDF] Acute respiratory distress syndrome: evaluation and management

I Cortés, O Peñuelas, A Esteban - Minerva Anestesiol, 2012 - researchgate.net
Acute respiratory distress syndrome (ARDS) is a life-threatening condition that affects
patients admitted in the Intensive Care Units (ICUs) under mechanical ventilation. ARDS is a …

Acute respiratory distress syndrome: advances in diagnosis and treatment

E Fan, D Brodie, AS Slutsky - Jama, 2018 - jamanetwork.com
Importance Acute respiratory distress syndrome (ARDS) is a life-threatening form of
respiratory failure that affects approximately 200 000 patients each year in the United States …

The acute respiratory distress syndrome: pathogenesis and treatment

MA Matthay, RL Zemans - Annual Review of Pathology …, 2011 - annualreviews.org
The acute respiratory distress syndrome (ARDS) causes 40% mortality in approximately
200,000 critically ill patients annually in the United States. ARDS is caused by protein-rich …

Treatment of ARDS

RG Brower, LB Ware, Y Berthiaume, MA Matthay - Chest, 2001 - Elsevier
Improved understanding of the pathogenesis of acute lung injury (ALI)/ARDS has led to
important advances in the treatment of ALI/ARDS, particularly in the area of ventilator …