The growing shortage of available organs is a major problem in transplantology. Thus, new
and alternative sources of organs need to be found. One promising solution could be …

The study of animal immune physiology and animal models of human disease have
accelerated many aspects of translational research by allowing direct, definitive …

Mice are arguably the experimental workhorse of immunological research and mouse
models have paved the way for the discovery of numerous important mechanisms related to …

At birth the piglet's immune system is immature and it is dependent upon passive maternal
protection until weaning. The piglet's mucosal immune system develops over the first few …

The gastrointestinal tract of mammals contains a complex microbial community that
influences numerous aspects of health and development. It is postulated that establishment …

In this article the anatomical structure of the porcine immune organs is described. The focus
is on their particularities that are related to the use of pigs as an animal model. Key issues of …

The ability to identify factors responsible for disease in all species depends on the ability to
separate those factors which are environmental from those that are intrinsic. This is …

The gastrointestinal tract (GIT) of adult mammals is colonized by a complex and dynamic
community of microorganisms. Most protection against potential pathogens occurs via a …

There are a large number of microorganisms in the porcine intestinal tract. These
microorganisms and their metabolites contribute to intestinal mucosal immunity, which is of …

Binding of natural anti-pig antibodies in humans and nonhuman primates to carbohydrate
antigens expressed on the transplanted pig organ, the most important of which is galactose …