Purpose Ischemia and reperfusion injury (I/R) of neuronal structures and organs is
associated with increased morbidity and mortality due to neuronal cell death. We …

Purpose.: Retinal ischemia/reperfusion (I/R) injury damages retinal neurons. Carbon
monoxide (CO) recently attracted attention as cytoprotective because of its anti-inflammatory …

Purpose Ischemia and reperfusion (I/R) injury damages retinal neurons. Retinal injury is
accompanied by activation of microglia, which scavenge the dead or dying neurons, but …

Purpose Retinal ischemia induces apoptosis leading to neurodegeneration and vision
impairment. Carbon monoxide (CO) in gaseous form showed cell-protective and anti …

In this study we tested the hypothesis that hyperbaric oxygen preconditioning (HBO-PC)
reduces retinal neuronal death due to optic nerve crush (ONC). Adult male Sprague-Dawley …

Purpose.: To investigate the effect of hyperbaric oxygen (HBO) chamber treatment in mouse
models of retinal ischemia. Methods.: Unilateral central retinal artery occlusion (CRAO) or …

Glaucomatous optic neuropathy, including axonal degeneration and apoptotic death of
retinal ganglion cells (RGCs), eventually leads to irreversible visual impairment. Carbon …

Traumatic optic neuropathy (TON) is characterized by visual dysfunction after indirect or
direct injury to the optic nerve following blunt head trauma. TON is associated with increased …

Purpose Retinal ischemia and reperfusion injuries (IRI) permanently affect neuronal tissue
and function by apoptosis and inflammation due to the limited regenerative potential of …

Purpose Retinal ischemia/reperfusion (I/R) injury plays an important role in the
pathophysiology of various ocular diseases. Retinal ganglion cells (RGCs) are particularly …