Mechanisms of mitochondrial iron-sulfur protein biogenesis
R Lill, SA Freibert - Annual review of biochemistry, 2020 - annualreviews.org
Mitochondria are essential in most eukaryotes and are involved in numerous biological
functions including ATP production, cofactor biosyntheses, apoptosis, lipid synthesis, and …
functions including ATP production, cofactor biosyntheses, apoptosis, lipid synthesis, and …
Iron–sulfur cluster biogenesis and trafficking in mitochondria
JJ Braymer, R Lill - Journal of Biological Chemistry, 2017 - ASBMB
The biogenesis of iron–sulfur (Fe/S) proteins in eukaryotes is a multistage,
multicompartment process that is essential for a broad range of cellular functions, including …
multicompartment process that is essential for a broad range of cellular functions, including …
[HTML][HTML] The role of mitochondria in cellular iron–sulfur protein biogenesis and iron metabolism
Mitochondria play a key role in iron metabolism in that they synthesize heme, assemble iron–
sulfur (Fe/S) proteins, and participate in cellular iron regulation. Here, we review the latter …
sulfur (Fe/S) proteins, and participate in cellular iron regulation. Here, we review the latter …
[HTML][HTML] Mechanisms of iron–sulfur protein maturation in mitochondria, cytosol and nucleus of eukaryotes
R Lill, R Dutkiewicz, HP Elsässer, A Hausmann… - … et Biophysica Acta (BBA …, 2006 - Elsevier
Iron–sulfur (Fe/S) clusters are important cofactors of numerous proteins involved in electron
transfer, metabolic and regulatory processes. In eukaryotic cells, known Fe/S proteins are …
transfer, metabolic and regulatory processes. In eukaryotic cells, known Fe/S proteins are …
The role of mitochondria in cellular iron–sulfur protein biogenesis: mechanisms, connected processes, and diseases
O Stehling, R Lill - Cold Spring Harbor perspectives in …, 2013 - cshperspectives.cshlp.org
Iron–sulfur (Fe/S) clusters belong to the most ancient protein cofactors in life, and fulfill
functions in electron transport, enzyme catalysis, homeostatic regulation, and sulfur …
functions in electron transport, enzyme catalysis, homeostatic regulation, and sulfur …
From the discovery to molecular understanding of cellular iron-sulfur protein biogenesis
R Lill - Biological chemistry, 2020 - degruyter.com
Protein cofactors often are the business ends of proteins, and are either synthesized inside
cells or are taken up from the nutrition. A cofactor that strictly needs to be synthesized by …
cells or are taken up from the nutrition. A cofactor that strictly needs to be synthesized by …
Iron-sulfur protein biogenesis in eukaryotes: components and mechanisms
R Lill, U Mühlenhoff - Annu. Rev. Cell Dev. Biol., 2006 - annualreviews.org
Abstract Iron-sulfur (Fe/S) clusters require a complex set of proteins to become assembled
and incorporated into apoproteins in a living cell. Researchers have described three distinct …
and incorporated into apoproteins in a living cell. Researchers have described three distinct …
Isa1p is a component of the mitochondrial machinery for maturation of cellular iron-sulfur proteins and requires conserved cysteine residues for function
A Kaut, H Lange, K Diekert, G Kispal, R Lill - Journal of Biological Chemistry, 2000 - ASBMB
In eukaryotes, mitochondria execute a central task in the assembly of cellular iron-sulfur
(Fe/S) proteins. The organelles synthesize their own set of Fe/S proteins, and they initiate …
(Fe/S) proteins. The organelles synthesize their own set of Fe/S proteins, and they initiate …
Iron–sulfur-protein biogenesis in eukaryotes
R Lill, U Mühlenhoff - Trends in biochemical sciences, 2005 - cell.com
Iron–sulfur (Fe–S) clusters (ISCs) are versatile, ancient co-factors of proteins that are
involved in electron transport, enzyme catalysis and regulation of gene expression. The …
involved in electron transport, enzyme catalysis and regulation of gene expression. The …
Mitochondrial iron–sulfur protein biogenesis and human disease
O Stehling, C Wilbrecht, R Lill - Biochimie, 2014 - Elsevier
Work during the past 14 years has shown that mitochondria are the primary site for the
biosynthesis of iron–sulfur (Fe/S) clusters. In fact, it is this process that renders mitochondria …
biosynthesis of iron–sulfur (Fe/S) clusters. In fact, it is this process that renders mitochondria …