[HTML][HTML] A controlled impact of optic nerve as a new model of traumatic optic neuropathy in mouse
AS Ibrahim, K Elmasry, M Wan… - … & Visual Science, 2018 - jov.arvojournals.org
Purpose: Traumatic optic neuropathy (TON) is the most feared visual consequence of head
and ocular trauma in both military and civilian communities, for which standard treatment …
and ocular trauma in both military and civilian communities, for which standard treatment …
[HTML][HTML] RGC and vision loss from traumatic optic neuropathy induced by repetitive closed head trauma is dependent on timing and force of impact
RS Khan, AG Ross, P Aravand, K Dine… - … vision science & …, 2021 - tvst.arvojournals.org
Purpose: Traumatic optic neuropathy (TON) is often caused by blunt head trauma and has
no currently effective treatment. Common animal models of TON induced by surgical crush …
no currently effective treatment. Common animal models of TON induced by surgical crush …
Establishment of a minimally invasive distal traumatic optic neuropathy model in mice to investigate cascade reactions of retinal glial cells
B Shen, H Yu, M Zhang, J Chen, Y Zhang… - The FASEB …, 2023 - Wiley Online Library
Traumatic optic neuropathy (TON) is a complication of craniocerebral, orbital and facial
injuries, leading to irreversible vision loss. At present, there is no reliable, widely used …
injuries, leading to irreversible vision loss. At present, there is no reliable, widely used …
[HTML][HTML] Traumatic Optic Neuropathy: Challenges and Opportunities in Developing Neuroprotective and Neuroregenerative Therapies
Despite years of basic science and clinical research, no treatment for TON exists. The
absence of therapies highlights the importance of a comprehensive understanding of …
absence of therapies highlights the importance of a comprehensive understanding of …
[HTML][HTML] Traumatic optic neuropathy is associated with visual impairment, neurodegeneration, and endoplasmic reticulum stress in adolescent mice
SM Hetzer, F Guilhaume-Correa, D Day, A Bedolla… - Cells, 2021 - mdpi.com
Traumatic brain injury (TBI) results in a number of impairments, often including visual
symptoms. In some cases, visual impairments after head trauma are mediated by traumatic …
symptoms. In some cases, visual impairments after head trauma are mediated by traumatic …
[HTML][HTML] Progression and pathology of traumatic optic neuropathy from repeated primary blast exposure
A Bernardo-Colón, V Vest, ML Cooper… - Frontiers in …, 2019 - frontiersin.org
Indirect traumatic optic neuropathy (ITON) is a condition that is often associated with
traumatic brain injury and can result in significant vision loss due to degeneration of retinal …
traumatic brain injury and can result in significant vision loss due to degeneration of retinal …
[HTML][HTML] Chronic histological outcomes of indirect traumatic optic neuropathy in adolescent mice: Persistent degeneration and temporally regulated glial responses
SM Hetzer, EM Shalosky, JN Torrens, NK Evanson - Cells, 2021 - mdpi.com
Injury to the optic nerve, termed, traumatic optic neuropathy (TON) is a known comorbidity of
traumatic brain injury (TBI) and is now known to cause chronic and progressive retinal …
traumatic brain injury (TBI) and is now known to cause chronic and progressive retinal …
Indirect traumatic optic neuropathy after head trauma in adolescent male mice is associated with behavioral visual impairment, neurodegeneration, and elevated …
SM Cansler, F Guilhaume-Correa, D Day, A Bedolla… - bioRxiv, 2020 - biorxiv.org
Traumatic brain injury (TBI) results in a number of impairments, often including visual
symptoms. In some cases, visual symptoms after head trauma are mediated by traumatic …
symptoms. In some cases, visual symptoms after head trauma are mediated by traumatic …
[HTML][HTML] Optic tract injury after closed head traumatic brain injury in mice: A model of indirect traumatic optic neuropathy
NK Evanson, F Guilhaume-Correa, JP Herman… - PLoS …, 2018 - journals.plos.org
Adult male C57BL/6J mice have previously been reported to have motor and memory
deficits after experimental closed head traumatic brain injury (TBI), without associated gross …
deficits after experimental closed head traumatic brain injury (TBI), without associated gross …
Evaluation of the neuroprotective effects of methylprednisolone and surgical decompression in a rodent model of traumatic optic neuropathy
P Korn, NC Gellrich, S Spalthoff, P Jehn… - Current Eye …, 2022 - Taylor & Francis
Purpose of the study Traumatic optic neuropathy (TON) is a rare but serious consequence of
head injuries. The optimal therapy for TON remains controversial, and standardized …
head injuries. The optimal therapy for TON remains controversial, and standardized …