Emerging evidence has demonstrated that melatonin (MT) plays a crucial role in regulating
mammalian reproductive functions. It has been reported that MT has a protective effect on …

Oxybenzone (OBZ), an ultraviolet light filter that is widely used in sunscreens and cosmetics,
is an emerging contaminant found in humans and the environment. Recent studies have …

If fertilization does not occur for a prolonged period in vivo or in vitro, the postovulatory
oocytes will deteriorate, which called the postovulatory aging. This process disrupts the …

Mammalian oocytes rely heavily on mitochondrial oxidative phosphorylation (OXPHOS) for
generating ATP. However, mitochondria are also the primary source of damaging reactive …

Objective: To establish an oxidative stress-induced model of premature ovarian insufficiency
(POI) and to explore the effect of SIRT1 and mitochondrial oxidative phosphorylation on the …

Hexestrol (HES) is a synthetic non-steroidal estrogen that was widely used illegally to boost
the growth rate in livestock production and aquaculture. HES can also be transferred to …

Psychological stress, which exerts detrimental effects on human reproduction, may
compromise the meiotic competence of oocytes. Meiotic resumption, germinal vesicle …

Mitochondrial division inhibitor 1 (Mdivi-1) reportedly provides a close connection between
oocyte maturation and mitochondrial function in pigs. N-acetyl-5-methoxy-tryptamine …

Mitochondria, the versatile organelles crucial for cellular and organismal viability, play a
pivotal role in meeting the energy requirements of cells through the respiratory chain located …

Oxidative-stress-induced apoptosis of granulosa cells is considered to be a main driver of
follicular atresia. Increasing evidence suggests a protective effect of melatonin against …