Alzheimer's disease (AD), an irreversible neurodegenerative disease that progressively
impairs memory and cognitive judgment, severely affects the quality of life and imposes a …

Alzheimer's disease (AD) is an incurable neurodegenerative disease affecting over 45
million people worldwide. Transgenic mouse models have made remarkable contributions …

Alzheimer disease (AD) is the leading cause of dementia among elderly. Currently, no
effective treatment is available for AD. Analysis of transgenic mouse models of AD has …

Alzheimer disease (AD) is a medically and financially overwhelming condition, and
incidence rates are expected to triple by 2050. Despite decades of research in animal …

Over 5 million Americans and 50 million individuals worldwide are living with Alzheimer's
disease (AD). The progressive dementia associated with AD currently has no cure. Although …

Alzheimer's disease (AD) impairs memory and causes significant cognitive deficits. The
disease course is prolonged, with a poor prognosis, and thus exacts an enormous economic …

A large number of mouse models have been engineered, characterized and used to
advance biomedical research in Alzheimer disease (AD). Early models simply damaged the …

Dementia of the Alzheimer type (AD) is clinically characterized by a progressive
deterioration of intellect, memory, judgment, and abstract thinking. It is incurable, and causal …

Animal models are indispensable tools for Alzheimer disease (AD) research. Over the
course of more than two decades, an increasing number of complementary rodent models …

Abstract Alzheimer's disease (AD), for which there is no cure, is the most common form of
dementia in the elderly. Despite tremendous efforts by the scientific community, the AD drug …