[HTML][HTML] Platelet-released extracellular vesicles: the effects of thrombin activation

R Suades, T Padró, G Vilahur, L Badimon - Cellular and Molecular Life …, 2022 - Springer
Platelets exert fundamental roles in thrombosis, inflammation, and angiogenesis,
contributing to different pathologies from cardiovascular diseases to cancer. We previously …

[HTML][HTML] Proteomic and functional profiling of platelet-derived extracellular vesicles released under physiological or tumor-associated conditions

M Vismara, M Manfredi, M Zarà, SMG Trivigno… - Cell Death …, 2022 - nature.com
During hemostasis, thrombosis, and inflammation, activated blood platelets release
extracellular vesicles (PEVs) that represent biological mediators of physiological and …

Dissecting the biochemical architecture and morphological release pathways of the human platelet extracellular vesiculome

SH De Paoli, TZ Tegegn, OK Elhelu, MB Strader… - Cellular and molecular …, 2018 - Springer
Platelet extracellular vesicles (PEVs) have emerged as potential mediators in intercellular
communication. PEVs exhibit several activities with pathophysiological importance and may …

[HTML][HTML] Extracellular vesicles from activated platelets possess a phospholipid-rich biomolecular profile and enhance prothrombinase activity

EM Guerreiro, SG Kruglik, S Swamy… - Journal of Thrombosis …, 2024 - Elsevier
Abstract Background Extracellular vesicles (EVs), in particular those derived from activated
platelets, are associated with a risk of future venous thromboembolism. Objectives To study …

Platelet extracellular vesicles: beyond the blood

F Puhm, E Boilard, KR Machlus - Arteriosclerosis, thrombosis, and …, 2021 - Am Heart Assoc
Extracellular vesicles (EVs) are a means of cell-to-cell communication and can facilitate the
exchange of a broad array of molecules between adjacent or distant cells. Platelets are …

[HTML][HTML] The pathophysiological role of platelet-derived extracellular vesicles

M Mabrouk, F Guessous, A Naya… - … in thrombosis and …, 2023 - thieme-connect.com
Platelets are very abundant in the blood, where they play a role in hemostasis, inflammation,
and immunity. When activated, platelets undergo a conformational change that allows the …

Isolation and characterization of platelet-derived extracellular vesicles

MT Aatonen, T Öhman, TA Nyman… - Journal of …, 2014 - Taylor & Francis
Background Platelet-derived extracellular vesicles (EVs) participate, for example, in
haemostasis, immunity and development. Most studies of platelet EVs have targeted …

Platelet-derived extracellular vesicles

A Gasecka, R Nieuwland, PRM Siljander - Platelets, 2019 - Elsevier
Platelet-derived extracellular vesicles (EVs) is a term that encompasses a heterogeneous
population of small membrane-enclosed vesicles containing a rich molecular cargo …

[HTML][HTML] The role of platelet-derived extracellular vesicles in immune-mediated thrombosis

AS Eustes, S Dayal - International journal of molecular sciences, 2022 - mdpi.com
Platelet-derived extracellular vesicles (PEVs) play important roles in hemostasis and
thrombosis. There are three major types of PEVs described based on their size and …

[HTML][HTML] Different potential of extracellular vesicles to support thrombin generation: contributions of phosphatidylserine, tissue factor, and cellular origin

C Tripisciano, R Weiss, T Eichhorn, A Spittler… - Scientific reports, 2017 - nature.com
Cells release diverse types of vesicles constitutively or in response to proliferation, injury,
inflammation, or stress. Extracellular vesicles (EVs) are crucial in intercellular …