Targeted analysis of dyslexia-associated regions on chromosomes 6, 12 and 15 in large multigenerational cohorts
NH Chapman, P Navas, MO Dorschner, M Mehaffey… - bioRxiv, 2023 - biorxiv.org
Dyslexia is a common specific learning disability with a strong genetic basis that affects word
reading and spelling. An increasing list of loci and genes have been implicated, but …
reading and spelling. An increasing list of loci and genes have been implicated, but …
[HTML][HTML] Discovery of 42 genome-wide significant loci associated with dyslexia
Reading and writing are crucial life skills but roughly one in ten children are affected by
dyslexia, which can persist into adulthood. Family studies of dyslexia suggest heritability up …
dyslexia, which can persist into adulthood. Family studies of dyslexia suggest heritability up …
Distinct impact modes of polygenic disposition to dyslexia in the adult brain
Dyslexia is a common condition that impacts reading ability. Identifying affected brain
networks has been hampered by limited sample sizes of imaging case-control studies. We …
networks has been hampered by limited sample sizes of imaging case-control studies. We …
[HTML][HTML] Association analysis of dyslexia candidate genes in a Dutch longitudinal sample
Dyslexia is a common specific learning disability with a substantive genetic component.
Several candidate genes have been proposed to be implicated in dyslexia susceptibility …
Several candidate genes have been proposed to be implicated in dyslexia susceptibility …
Dense‐map genome scan for dyslexia supports loci at 4q13, 16p12, 17q22; suggests novel locus at 7q36
LL Field, K Shumansky, J Ryan… - Genes, Brain and …, 2013 - Wiley Online Library
Analysis of genetic linkage to dyslexia was performed using 133,165 array‐based SNPs
genotyped in 718 persons from 101 dyslexia‐affected families. Results showed five linkage …
genotyped in 718 persons from 101 dyslexia‐affected families. Results showed five linkage …
[HTML][HTML] Genetic analysis of dyslexia candidate genes in the European cross-linguistic NeuroDys cohort
Dyslexia is one of the most common childhood disorders with a prevalence of around 5–
10% in school-age children. Although an important genetic component is known to have a …
10% in school-age children. Although an important genetic component is known to have a …
[HTML][HTML] Polymorphisms in DCDC2 and S100B associate with developmental dyslexia
H Matsson, M Huss, H Persson, E Einarsdottir… - Journal of human …, 2015 - nature.com
Genetic studies of complex traits have become increasingly successful as progress is made
in next-generation sequencing. We aimed at discovering single nucleotide variation present …
in next-generation sequencing. We aimed at discovering single nucleotide variation present …
Molecular genetics of dyslexia: an overview
Dyslexia is a highly heritable learning disorder with a complex underlying genetic
architecture. Over the past decade, researchers have pinpointed a number of candidate …
architecture. Over the past decade, researchers have pinpointed a number of candidate …
[HTML][HTML] Insights into dyslexia genetics research from the last two decades
Dyslexia, a specific reading disability, is a common (up to 10% of children) and highly
heritable (~ 70%) neurodevelopmental disorder. Behavioral and molecular genetic …
heritable (~ 70%) neurodevelopmental disorder. Behavioral and molecular genetic …
[HTML][HTML] Genome-wide association study reveals new insights into the heritability and genetic correlates of developmental dyslexia
A Gialluisi, TFM Andlauer, N Mirza-Schreiber… - Molecular …, 2021 - nature.com
Developmental dyslexia (DD) is a learning disorder affecting the ability to read, with a
heritability of 40–60%. A notable part of this heritability remains unexplained, and large …
heritability of 40–60%. A notable part of this heritability remains unexplained, and large …