Targeted analysis of dyslexia-associated regions on chromosomes 6, 12 and 15 in large multigenerational cohorts

NH Chapman, P Navas, MO Dorschner, M Mehaffey… - bioRxiv, 2023 - biorxiv.org
Dyslexia is a common specific learning disability with a strong genetic basis that affects word
reading and spelling. An increasing list of loci and genes have been implicated, but …

[HTML][HTML] Discovery of 42 genome-wide significant loci associated with dyslexia

C Doust, P Fontanillas, E Eising, SD Gordon, Z Wang… - Nature …, 2022 - nature.com
Reading and writing are crucial life skills but roughly one in ten children are affected by
dyslexia, which can persist into adulthood. Family studies of dyslexia suggest heritability up …

Distinct impact modes of polygenic disposition to dyslexia in the adult brain

S Soheili-Nezhad, D Schijven, RB Mars, SE Fisher… - medRxiv, 2024 - medrxiv.org
Dyslexia is a common condition that impacts reading ability. Identifying affected brain
networks has been hampered by limited sample sizes of imaging case-control studies. We …

[HTML][HTML] Association analysis of dyslexia candidate genes in a Dutch longitudinal sample

A Carrion-Castillo, B Maassen, B Franke… - European Journal of …, 2017 - nature.com
Dyslexia is a common specific learning disability with a substantive genetic component.
Several candidate genes have been proposed to be implicated in dyslexia susceptibility …

Dense‐map genome scan for dyslexia supports loci at 4q13, 16p12, 17q22; suggests novel locus at 7q36

LL Field, K Shumansky, J Ryan… - Genes, Brain and …, 2013 - Wiley Online Library
Analysis of genetic linkage to dyslexia was performed using 133,165 array‐based SNPs
genotyped in 718 persons from 101 dyslexia‐affected families. Results showed five linkage …

[HTML][HTML] Genetic analysis of dyslexia candidate genes in the European cross-linguistic NeuroDys cohort

J Becker, D Czamara, TS Scerri, F Ramus… - European Journal of …, 2014 - nature.com
Dyslexia is one of the most common childhood disorders with a prevalence of around 5–
10% in school-age children. Although an important genetic component is known to have a …

[HTML][HTML] Polymorphisms in DCDC2 and S100B associate with developmental dyslexia

H Matsson, M Huss, H Persson, E Einarsdottir… - Journal of human …, 2015 - nature.com
Genetic studies of complex traits have become increasingly successful as progress is made
in next-generation sequencing. We aimed at discovering single nucleotide variation present …

Molecular genetics of dyslexia: an overview

A Carrion‐Castillo, B Franke, SE Fisher - Dyslexia, 2013 - Wiley Online Library
Dyslexia is a highly heritable learning disorder with a complex underlying genetic
architecture. Over the past decade, researchers have pinpointed a number of candidate …

[HTML][HTML] Insights into dyslexia genetics research from the last two decades

F Erbeli, M Rice, S Paracchini - Brain Sciences, 2021 - mdpi.com
Dyslexia, a specific reading disability, is a common (up to 10% of children) and highly
heritable (~ 70%) neurodevelopmental disorder. Behavioral and molecular genetic …

[HTML][HTML] Genome-wide association study reveals new insights into the heritability and genetic correlates of developmental dyslexia

A Gialluisi, TFM Andlauer, N Mirza-Schreiber… - Molecular …, 2021 - nature.com
Developmental dyslexia (DD) is a learning disorder affecting the ability to read, with a
heritability of 40–60%. A notable part of this heritability remains unexplained, and large …