Despite the devastation caused by the human immunodeficiency virus (HIV) for over four
decades, a subset of individuals termed HIV-1 elite controllers (ECs) can control the virus in …

Methods and Results: The function and phenotype of NK cells were investigated using 10-
color flow cytometry. Surprisingly, NK cells displayed elevated production of interferon-γ and …

Background We examined NK cell phenotypes and functions after seven years of ART and
undetectable viral loads (< 50 copies/ml) with restored CD4 T-cell counts (≥ 500 cells/μl) …

Objective: Of the predominant HIV-1 subtypes in Uganda, subtype D infection confers a
worse prognosis. HIV-1 infection causes perturbations to natural killer (NK) cells, and yet …

Progression to AIDS during HIV-infection is associated with a decrease in the number and
function of natural killer (NK) cells [1–4]. The reduction in NK cells expressing CD56 and …

HIV-1 viremia has been shown to induce several phenotypic and functional abnormalities in
natural killer (NK) cells. To assess immune defects associated with HIV viremia, we …

Recent studies suggest that innate immune responses by natural killer (NK) cells play a
significant role in restricting human immunodeficiency virus type-1 (HIV-1) pathogenesis …

Phenotypic changes and functional impairment of natural killer (NK) cells occur early in HIV-
1 infection. Antiretroviral therapy (ART) effectively restores CD4+ T cell counts and …

Innate immunity may play a role in preventing HIV infection and progression to AIDS. Most
studies of natural killer (NK) cell function have been conducted in populations with different …

Natural killer (NK) cell plays an important role in an innate immune response against viral
infection. The kinetics regulation and functional consequences of NK cells in the …