Candida Glabrata Produces a Melanin-Like Pigment that Protects Against Stress Conditions Encountered During Parasitism

R Almeida-Paes, MHG Figueiredo-Carvalho… - Future …, 2021 - Taylor & Francis
Aim: Melanin has been linked to pathogenesis in several fungi. They often produce melanin-
like pigments in the presence of L-dihydroxyphenylalanine (L-DOPA), but this is poorly …

Antifungal activity of melanin in clinical isolates of Candida spp

M Fuentes, R Hernandez, D Gordillo… - Revista Chilena de …, 2014 - europepmc.org
[Antifungal activity of melanin in clinical isolates of Candida spp]. - Abstract - Europe PMC Sign
in | Create an account https://orcid.org Europe PMC Menu About Tools Developers Help …

Melanin externalization in Candida albicans depends on cell wall chitin structures

CA Walker, BL Gómez, HM Mora-Montes… - Eukaryotic …, 2010 - Am Soc Microbiol
The fungal pathogen Candida albicans produces dark-pigmented melanin after 3 to 4 days
of incubation in medium containing l-3, 4-dihydroxyphenylalanine (l-DOPA) as a substrate …

Melanization of Candida auris Is Associated with Alteration of Extracellular pH

DFQ Smith, NJ Mudrak, D Zamith-Miranda, L Honorato… - Journal of Fungi, 2022 - mdpi.com
Candida auris is a recently emerged global fungal pathogen, which causes life-threatening
infections, often in healthcare settings. C. auris infections are worrisome because the fungus …

[HTML][HTML] Melanin in the dimorphic fungal pathogen Paracoccidioides brasiliensis: effects on phagocytosis, intracellular resistance and drug susceptibility

MB Da Silva, AF Marques, JD Nosanchuk… - Microbes and …, 2006 - Elsevier
The fungal pathogen Paracoccidioides brasiliensis produces a melanin-like pigment in the
presence of l-DOPA in vitro. We investigated whether melanization affected yeast uptake by …

Does DHN-Melanin Always Protect Fungi against Antifungal Drugs? The Fonsecaea/Micafungin Paradigm

RA Coelho, MHG Figueiredo-Carvalho, JVS Silva… - Microbiology …, 2022 - mdpi.com
Several human pathogenic fungi produce melanin. One of its properties during parasitism is
the protection against antifungal drugs. This occurs with the agents of chromoblastomycosis …

The role of melanin in fungal disease

RP Baker, A Casadevall, E Camacho… - Melanins: Functions …, 2023 - Springer
Many fungi produce melanins, which can play critical roles in virulence and pathogenicity. In
fungal pathogenic species, melanin confers protection against host immune defense …

Galleria mellonella immune melanization is fungicidal during infection

DFQ Smith, Q Dragotakes, M Kulkarni… - Communications …, 2022 - nature.com
A key component of the insect immune response is melanin production, including within
nodules, or aggregations of immune cells surrounding microbes. Melanization produces …

Melanin from Fonsecaea pedrosoi Induces Production of Human Antifungal Antibodies and Enhances the Antimicrobial Efficacy of Phagocytes

DS Alviano, AJ Franzen, LR Travassos… - Infection and …, 2004 - Am Soc Microbiol
Fonsecaea pedrosoi is a fungal pathogen that produces melanin. The functions of melanin
and its possible influence in the protective immunological response during infection by F …

L-DOPA accessibility in culture medium increases melanin expression and virulence of Sporothrix schenckii yeast cells

PAC Teixeira, RA De Castro, FRL Ferreira… - Medical …, 2010 - academic.oup.com
Melanin is a complex polymer widely distributed in nature and has been described as an
important virulence factor in several pathogenic fungi, including Sporothrix schenckii. The …