[HTML][HTML] Type 2 diabetes subgroups and potential medication strategies in relation to effects on insulin resistance and beta-cell function: A step toward personalised …
A Veelen, E Erazo-Tapia, J Oscarsson… - Molecular Metabolism, 2021 - Elsevier
Background Type 2 diabetes is a syndrome defined by hyperglycaemia that is the result of
various degrees of pancreatic β-cell failure and reduced insulin sensitivity. Despite the fact …
various degrees of pancreatic β-cell failure and reduced insulin sensitivity. Despite the fact …
Type 2 diabetes: a multifaceted disease
ER Pearson - Diabetologia, 2019 - Springer
Type 2 diabetes is a complex disease usually diagnosed with little regard to aetiology. In the
broader sense, it is a mix of different clearly defined aetiologies, such as monogenic …
broader sense, it is a mix of different clearly defined aetiologies, such as monogenic …
What is type 2 diabetes?
G Smushkin, A Vella - Medicine, 2010 - Elsevier
Type 2 diabetes is a common metabolic disorder characterized by chronic hyperglycaemia.
It is associated with a reduced life expectancy owing to a greater risk of heart disease …
It is associated with a reduced life expectancy owing to a greater risk of heart disease …
Changing perspectives in diabetes: their impact on its classification
TJ Wilkin - Diabetologia, 2007 - Springer
Type 1 and type 2 diabetes are usually regarded as distinct disorders, but the convergence
of their phenotypes over recent years, the relationship of body weight to the risk of type 1 …
of their phenotypes over recent years, the relationship of body weight to the risk of type 1 …
“H” for heterogeneity in the algorithm for type 2 diabetes management
P Silvia, Z Simona, M Ernesto, B Raffaella - Current diabetes reports, 2020 - Springer
Abstract Purpose of Review Genetic, socioeconomic and clinical features vary considerably
among individuals with type 2 diabetes (T2D) influencing disease development, progression …
among individuals with type 2 diabetes (T2D) influencing disease development, progression …
Type 1 diabetes: A new vision of the disease based on endotypes
CS Weston, BO Boehm, P Pozzilli - … /Metabolism Research and …, 2024 - Wiley Online Library
Diagnosis and management of type 1 diabetes (T1D) have remained largely unchanged for
the last several years. The management of the disease remains primarily focused on its …
the last several years. The management of the disease remains primarily focused on its …
Pathophysiology of type 1 and type 2 diabetes mellitus: a 90-year perspective
Diabetes mellitus is a complex metabolic disorder associated with an increased risk of
microvascular and macrovascular disease; its main clinical characteristic is hyperglycaemia …
microvascular and macrovascular disease; its main clinical characteristic is hyperglycaemia …
Individualizing therapies in type 2 diabetes mellitus based on patient characteristics: what we know and what we need to know
RJ Smith, DM Nathan, SA Arslanian… - The Journal of …, 2010 - academic.oup.com
Objective: Type 2 diabetes is heterogeneous in its clinical features, pathogenesis, and
predisposing or causal genetic factors. This report examines what is known and what needs …
predisposing or causal genetic factors. This report examines what is known and what needs …
A roadmap to achieve pharmacological precision medicine in diabetes
JC Florez, ER Pearson - Diabetologia, 2022 - Springer
Current pharmacological treatment of diabetes is largely algorithmic. Other than for
cardiovascular disease or renal disease, where sodium–glucose cotransporter 2 inhibitors …
cardiovascular disease or renal disease, where sodium–glucose cotransporter 2 inhibitors …
Type 2 diabetes subgroups and response to glucose‐lowering therapy: Results from the EDICT and Qatar studies
T Abdul‐Ghani, C Puckett, O Migahid… - Diabetes, Obesity …, 2022 - Wiley Online Library
Aim To examine the efficacy of glucose‐lowering medications in subgroups of patients with
type 2 diabetes mellitus (T2DM). Research design and methods Cluster analysis was …
type 2 diabetes mellitus (T2DM). Research design and methods Cluster analysis was …