LncRNA-mediated regulation of cell signaling in cancer

WX Peng, P Koirala, YY Mo - Oncogene, 2017 - nature.com
To date, a large number of long non-coding RNAs (lncRNAs) have been recently discovered
through functional genomics studies. Importantly, lncRNAs have been shown, in many …

The functions and unique features of LncRNAs in cancer development and tumorigenesis

K Taniue, N Akimitsu - International journal of molecular sciences, 2021 - mdpi.com
Over the past decades, research on cancer biology has focused on the involvement of
protein-coding genes in cancer development. Long noncoding RNAs (lncRNAs), which are …

Long non-coding RNAs: Tools for understanding and targeting cancer pathways

GK Pandey, C Kanduri - Cancers, 2022 - mdpi.com
Simple Summary Long non-coding RNA (lncRNA) is a type of RNA molecule that show
striking resemblance to mRNA in terms of synthesis and structure but lacks protein coding …

[HTML][HTML] Functional roles of lncRNAs in the pathogenesis and progression of cancer

A Ahadi - Genes & Diseases, 2021 - Elsevier
Long noncoding RNAs (lncRNAs) act as regulators of gene expression and pivotal
transcriptional regulators in cancer cells via diverse mechanisms. lncRNAs involves a …

Molecular function and regulation of long non-coding RNAs: paradigms with potential roles in cancer

M Hajjari, A Khoshnevisan, YK Shin - Tumor Biology, 2014 - Springer
Different long non-coding RNAs (lncRNAs) are transcribed within the genome. Although
initially argued to be spurious transcriptional noise, these RNAs play important roles in …

[PDF][PDF] Long non-coding RNAs in cancer

MY Kim - Non-Coding RNA Research, 2019 - koasas.kaist.ac.kr
It is now well established that long non-coding RNAs (lncRNAs) are key regulators in
various biological processes such as development, metabolism and immune response …

Long non-coding RNAs in haematological malignancies

A Garitano-Trojaola, X Agirre, F Prósper… - International journal of …, 2013 - mdpi.com
Long non-coding RNAs (lncRNAs) are functional RNAs longer than 200 nucleotides in
length. LncRNAs are as diverse as mRNAs and they normally share the same biosynthetic …

[HTML][HTML] Long noncoding RNAs as promising biomarkers in cancer

O Beylerli, I Gareev, A Sufianov, T Ilyasova… - Non-coding RNA …, 2022 - Elsevier
Despite many advances in diagnosis and therapy (surgery, radiation therapy,
chemotherapy), cancer remains one of the most important public health problems …

[HTML][HTML] Long non-coding RNAs regulating multiple proliferative pathways in cancer cell

M De Martino, F Esposito, P Pallante - Translational cancer …, 2021 - ncbi.nlm.nih.gov
Long non-coding RNAs (lncRNAs) belong to an extremely heterogeneous class of non-
coding RNAs with a length ranging from 200 to 100,000 bp. They modulate a series of …

Targetable long non-coding RNAs in cancer treatments

L Chen, EE Dzakah, G Shan - Cancer letters, 2018 - Elsevier
Aberrant expression of many long non-coding RNAs has been observed in various types of
cancer, implicating their crucial roles in tumorigenesis and cancer progression. Emerging …