Abstract Background: Long noncoding RNAs (lncRNAs) are a novel type of endogenous
noncoding RNA that are involved in the regulation of gene expression and play important …

Chemoresistance, whether intrinsic or acquired, is a major obstacle in the treatment of
cancer. The resistance of cancer cells to chemotherapeutic drugs can result from various …

Angiogenesis has critical roles in numerous physiologic processes during embryonic and
adult life such as wound healing and tissue regeneration. However, aberrant angiogenic …

Long non-coding RNAs (lncRNAs), a group of non-protein-coding RNAs longer than 200
nucleotides, are involved in multiple biological and pathological processes, such as …

Dysregulation of gene expression, often interpreted by gene transcription as an endpoint
response, is tightly associated with human cancer. Long noncoding RNAs (lncRNAs) …

Long non-coding RNAs (ncRNAs) have been shown to regulate important biological
processes that support normal cellular functions. Aberrant regulation of these essential …

Long non-coding RNAs (lncRNAs) represent a significant population of the human
transcriptome. Many lncRNAs exhibit cell-and/or tissue/tumor-specific expression, making …

The resistance of cancer cells to anti-cancer drugs is an important reason for the failure of
treatment. Overcoming drug resistance can achieve long-lasting and efficient cancer …

Pervasive transcription occurs in the human genome to generate thousands of RNA
transcripts, and accumulating evidence suggested that the RNA molecules, without protein …

Cancer cells acquire numerous biological properties (designated “cancer hallmarks”), such
as cell survival and energy metabolism, that facilitate tumor growth and metastatic …