Objective Despite the overall success of responsive neurostimulation (RNS) therapy for drug‐
resistant focal epilepsy, clinical outcomes in individuals vary significantly and are hard to …

Responsive neurostimulation (RNS) devices, able to detect imminent seizures and to rapidly
deliver electrical stimulation to the brain, are effective in reducing seizures in some patients …

Importance A bidirectional brain-computer interface that performs neurostimulation has been
shown to improve seizure control in patients with refractory epilepsy, but the therapeutic …

Responsive neurostimulation is a promising treatment for drug-resistant focal epilepsy;
however, clinical outcomes are highly variable across individuals. The therapeutic …

In patients with drug-resistant epilepsy, electrical stimulation of the brain in response to
epileptiform activity can make seizures less frequent and debilitating. This therapy, known as …

Introduction: Epilepsy affects more than 1% of the US population, and over 30% of adults
with epilepsy do not respond to antiseizure medications without life-impacting medication …

Closed-loop brain stimulation is increasingly used in level 4 epilepsy centers without an
understanding of how the device behaves on a daily basis. This lack of insight is a barrier to …

Objective Understanding the acute effects of responsive stimulation (AERS) based on
intracranial EEG (iEEG) recordings in ambulatory patients with drug-resistant partial …

Responsive neurostimulation (RNS) is an effective therapy for people with drug-resistant
focal epilepsy. In clinical trials, RNS therapy results in a meaningful reduction in median …

Objective Managing the progress of drug‐resistant epilepsy patients implanted with the
Responsive Neurostimulation (RNS) System requires the manual evaluation of hundreds of …