Promising biomarkers of human aging: In search of a multi-omics panel to understand the aging process from a multidimensional perspective

NA Rivero-Segura, OY Bello-Chavolla… - Ageing research …, 2020 - Elsevier
The aging process has been linked to the occurrence of chronic diseases and functional
impairments, including cancer, sarcopenia, frailty, metabolic, cardiovascular, and …

Aging biomarkers: from functional tests to multi‐omics approaches

KS Kudryashova, K Burka, AY Kulaga… - …, 2020 - Wiley Online Library
Aging results in various deleterious changes in the human body that may lead to loss of
function and the manifestation of chronic diseases. While diseases can generally be reliably …

[HTML][HTML] Molecular and phenotypic biomarkers of aging

X Xia, W Chen, J McDermott, JDJ Han - F1000Research, 2017 - ncbi.nlm.nih.gov
Individuals of the same age may not age at the same rate. Quantitative biomarkers of aging
are valuable tools to measure physiological age, assess the extent of 'healthy aging', and …

[HTML][HTML] Biomarkers of aging

Aging Biomarker Consortium, H Bao, J Cao… - Science China Life …, 2023 - Springer
Aging biomarkers are a combination of biological parameters to (i) assess age-related
changes,(ii) track the physiological aging process, and (iii) predict the transition into a …

Molecular and physiological manifestations and measurement of aging in humans

SS Khan, BD Singer, DE Vaughan - Aging cell, 2017 - Wiley Online Library
Biological aging is associated with a reduction in the reparative and regenerative potential
in tissues and organs. This reduction manifests as a decreased physiological reserve in …

Biomarkers of aging for the identification and evaluation of longevity interventions

M Moqri, C Herzog, JR Poganik, J Justice, DW Belsky… - Cell, 2023 - cell.com
With the rapid expansion of aging biology research, the identification and evaluation of
longevity interventions in humans have become key goals of this field. Biomarkers of aging …

[HTML][HTML] A proposed panel of biomarkers of healthy ageing

J Lara, R Cooper, J Nissan, AT Ginty, KT Khaw… - BMC medicine, 2015 - Springer
Background There is no criterion reference for assessing healthy ageing and this creates
difficulties when conducting and comparing research on ageing across studies. A cardinal …

Aging: the reality: biomarkers of aging: from primitive organisms to humans

RN Butler, R Sprott, H Warner, J Bland… - The Journals of …, 2004 - academic.oup.com
Leading biologists and clinicians interested in aging convened to discuss biomarkers of
aging. The goals were to come to a consensus, construct an agenda for future research, and …

Integration of 'omics' data in aging research: from biomarkers to systems biology

J Zierer, C Menni, G Kastenmüller, TD Spector - Aging cell, 2015 - Wiley Online Library
Age is the strongest risk factor for many diseases including neurodegenerative disorders,
coronary heart disease, type 2 diabetes and cancer. Due to increasing life expectancy and …

[HTML][HTML] Revisiting the hallmarks of aging to identify markers of biological age

F Guerville, P De Souto Barreto, I Ader… - The Journal of …, 2020 - Springer
The Geroscience aims at a better understanding of the biological processes of aging, to
prevent and/or delay the onset of chronic diseases and disability as well as to reduce the …